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There is certainly a naïvety in the suggestion that there are known effective approaches but I think it is important no to confuse a whole range of different issues here. I can answer that - because patients say so from their 'lived experience'. I have come across socially people who are...

Whatever one might think about the diagnosis of FND there are people who have problems that at present get put under that heading because nobody has a clue where else to put them. Some of them have symptoms that look like stroke but clearly do not have the upper motor neuron problems that are...

I don' think that we should be judging people by what they study, though, @Hutan. Sarah worked in rehabilitation and would have come across patients with the diagnosis of functional stroke - as the paper says. I have only looked at the abstract but it looks pretty good. This is a situation...

I don' think that we should be judging people by what they study, though, @Hutan. Sarah worked in rehabilitation and would have come across patients with the diagnosis of functional stroke - as the paper says. I have only looked at the abstract but it looks pretty good. This is a situation...

I had not bothered to look at these. This is not even usable data. It is a series of 'qualitative' studies that tell us nothing more than, to quote one ' Staff were generally positive about the toolkit' If this is what is aimed at there is no justification for funding it. I am afraid it is more...

I don't think this is an issue of distinguishing processes but distinguishing effects. I think it is saying: 'all the symptoms that occur immediately or in less than 12 hours following the exertion are called exercise intolerance'. They may or may not be associated with a process that can also...

That would be your CatGPT Large Language Model I guess?

That there is a list of well known secondary causes of hypertension that all medical students learn. In my day we screened for those things that were reasonably practical - full physical examination, renal chemistry, chest X ray, etc etc.. Not sure what the guidelines are these days.

That particular graph doesn't.

As Hutan has indicated this may in a sense be a question we cannot really pose or answer usefully. One answer that comes to mind is that we have no reliable evidence it isn't but then we have no reliable evidence it isn't due to aliens. We have reliable evidence it isn't due to mobile phones...

I am not quite sure what you are trying to get at. I realise it is complex and counterintuitive. The world consists of fields that 'advance' through spacetime stepwise through 'excitations' or 'changes' that used to be called 'particles' but are more 'actions'. For any pattern of the fields a...

Not really. I am talking about a logical necessity that Einstein understood very well. A lot of people don't like it because it spoils intuitive realism. But as a physician aI am very aware that the representational nature of our experiences makes intuitive realism a very bad place to start...

I agree. PEM would still be just as much PEM even if the CPETs had been plumb normal. Fatiguability is a distinct concept.

I do think that three people in a family all getting ME at the same time must be significant, though. There is nothing in the immune model as I understand it that would explain that. But there are always surprises in science where a simple mechanism one had not thought of can explain something...

Indeed there are processes for fixing the awareness and we know a lot about them. One is a process called receptor editing, which put rogue B cells back on a sensible track. Another is complement mediated deletion. Receptor editing is dependent on PTPN22, which is a risk factor for RA and...

It is not only left but it takes over the whole picture, hence the advance of entropy. There is a lot of intuitive resistance to the idea that fundamental events have to be partly random and that this is the reason why our world is awash with randomness but it has to be true. The most...

There aren't any 'wave functions' that collapse and any good quantum theoretician will tell you that. Once an excitation has occurred and annihilated (which they do do) you are left with the randomness caused by the necessary stochasticity of the occurrence. If every move on a chess board is a...

Aha! Dear Roger is very convinced of his ideas and they have had a good run in terms of fashionability but almost everyone now in the consciousness studies community reckons they don't add up. Interestingly, if you read his Shadows of the Mind you can see that, very much like Einstein, Roger...

I think the root of the rot may be this sentence: A core outcome set What core set of relevant health outcome measures should be used for trials of treatments for ME/CFS and managing symptoms of ME/CFS? It muddles trial outcome measures with management in exactly the way the project seems to...

I am not so sure. I have recently uploaded an article to the journal Qeios on the basis of what people call free will and discussed fundamental stochasticity there. It is actually entailed logically by the continuous nature of the spacetime metric, the discreteness of events and the...