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I have long thought that the mechanics of the ECM need some serious attention.

Within the first day of infection you have a metabolic profile which predicts the outcome, and that can be whether you recover, whether you get long COVID or whether you're going to die. This could be interesting. Predictive power at this level is good.

Thank you, Prof. :thumbsup:

I have been giving myself No. 2 buzz cuts for 20 years. Saves a lot of money and hair care.

Point taken. But poorly run observational studies is different from observational studies not being of any intrinsic value. I agree with this.

I think LC patients are expecting too much too quickly. I mean, they should be demanding good science on this, and lots of it. But effective clinically applicable results ain't gonna happen overnight.

They hate and fear us because our mere existence exposes their ignorance and incompetence, their technical and ethical bankruptcy, and the consequences of that for patients. Then we delusional peasant scum add insult to injury by proactively, and accurately, pointing all that out out to the...

A range of conditions including Guillain-Barré syndrome, @Snow Leopard

Not sure this is an important criticism. Half the studies being observational doesn't seem inappropriate for the initial assessment of an emerging problem. Or worse.

This.

Ultimately our fate is going to be decided by bean counters.

I am very firmly of the view that it is deliberate. They know what they are doing. It is entirely arse covering for their very serious sins during the 20 year reign of the current editor in chief, Horton, and will not change while he remains in the position.

Great news. Thanks to all who worked hard to bring this about. :):):):hug::hug::hug: That is literally true. But if I recall the history of this correctly, it should also be noted that it was the previous (and very conservative) government, presumably via their health minister, Greg Hunt, who...

Or the 'rest' it can get is very poor quality.

Doctors are not trained as scientists, though they flatter themselves that they are. They are trained as technicians, which they often forget. Engineering has a similar problem. Medicine is still trying to shake of its deeply embedded eminence based model, with limited success thus far. In...

Um, ah, er,... :speechless:

I guess when you don't have a robust evidence base then all you are left with is the marketing.

A few years back Australia medicos got their knickers in a twist about codeine based over the counter meds (with low levels of codeine 12-15mg, combined with 500mg paracetamol/acetaminophen), and got them made prescription only, and virtually impossible to get. It was a major overreaction to...

I am as critical of the NIH on a range of issues as anybody. But we do need to be careful about how we criticise them. There are ideological interests in this world unrelated to LC or ME/CFS, or health stuff in general, who want to basically kill the NIH and any government involvement, and they...

Their origin is multifactorial and poorly understood, If it is poorly understood, then how can they be sure it is multifactorial? and their management is often inadequately defined. Difficult to define something you don't understand, especially when you don't want to understand it. Not doing...