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FND is no longer a synonym for conversion disorder as many medical practitioners have abandoned the idea (due to a lack of evidence despite a century of looking) that symptoms are explained by "emotional charge" that is somehow "converted" into neurological symptoms as described by Freud. But...

Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel https://www.medrxiv.org/content/10.1101/2021.07.13.21260393v1 This is pre-delta, but I don't think delta would be much different.

https://clinicalstudies.info.nih.gov/ProtocolDetails.aspx?id=20-NR-0003 I don't understand why they think this. Both ketamine and midazolam will increase central fatigue. Edit - I think the expected mechanism is an analgesic effect... In the paper mentioned below, the authors speculate about...

It depends on the impairment and the type of rehabilitation. Work-focused rehabilitation, eg reduced hours is better than jumping straight back in once someone's sick leave finishes. Rehabilitation might be useful for those who have been hospitalised and have pulmonary impairment who have to...

Keeping in mind this patients who happened to attend a specific hospital, it is not an unbiased selection of patients. Only a prospective community-based study would lead to strong conclusions about the relationship between antibody response and Long Covid outcomes. The patients in general may...

Agreed. Too much reinvention of the wheel, as researchers pretend that this is magically different from ME/CFS and post-viral illness and thus are ignorant of prior research. I do worry that rehabilitation approaches will be misapplied - they can be helpful for patients who are spontaneously...

How about we ban wealthy people in having a say on tax increases?

That is due to risk of anaphylactic reaction, which is quite different to what the people in this study reported.

edit - I have read the paper now. The cases are unusual in that the patients claim symptoms appeared within 20 minutes of inoculation, but I cannot think of a mechanism that would cause the symptoms described that quickly. Also, note the note:

Which is weak evidence... Also, I'm not sure what the relevance of calcium channel function in NK Cells is to ME anyway. What occurs in leukocytes in circulation is not the same as what happens in other tissues... That said, it would be nice to have a proper double blinded LDN study, even if it...

"Rates"? The key is the severity. I've had a few friends who have had schizophrenia, their tiredness/lack of energy was mostly caused by a lack of sleep or medication side effects (or undiagnosed cancer causing a major hormone imbalance)...

It actually suggests the opposite - CK spills over into circulation when muscles are damaged. What it really means is patients are less active than controls.

I must admit I did a double take there. If their symptom reporting is highly biased, then the concept of "people high on medically unexplained symptoms" makes little sense.

It is an interesting hypothesis, but is very much of house-of-cards construction, requiring a lot of empirical validation steps that could easily turn out not to be true. I do note they've singled out a few things that I have previously talked about in my random/speculative ideas thread, that...

I'm getting a bit bored of these retrospective questionnaire based studies. Why didn't the CDC or anyone else step up to the plate with a prospective community based study? I mean they've had 18 months to get one started!?!

This is certainly curious, but I'd like to see independent replication by another lab before I get too excited.

When I was 16, I'd have written a very angry piece about the ignorance of doctors that would almost certainly have been rejected...

The other viruses have become endemic because societies have tolerated them. We can eliminate this one with global vaccination and quarantine if we choose to do so.

Yes, without any sort of theoretical specificity it is just pseudoscience.

It sounds like the individual is still ill, but is just better able to manage what energy they have by pacing. The stuff about "boom-bust" just sounds like parroting what they were taught by a therapist.