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Thanks, I was curious about the selection of the last two IAG members.

If replicated and built upon, this could be a big deal, but this is not guaranteed. It is interesting that they claim the IgG sensitised nerves but did not cause systemic inflammation or cytokine differences. They also found no effect in the spinal cord, suggesting it is a peripheral phenomena...

This study is doing the rounds as an "explanation" of why the viral vector vaccines have increased risk of the Thrombosis and Thrombocytopenia syndrome: https://www.biorxiv.org/content/10.1101/2021.06.29.450356v1.full.pdf They claim that the vaccine accidentally being injected into a vein...

That was the (currently most recent) Public Health England data. https://www.medrxiv.org/content/10.1101/2021.05.22.21257658v1 In prior research, efficacy against symptomatic infection has correlated reasonably well with transmission rates, hence I am willing to bet that the vaccines that have...

So what? All SARS-2 is highly infectious. I think naming these variants is often used to deflect blame from authorities...

There are worrying trends of a "third wave" (or is that fourth) in the UK, with cases per day per million almost ten times higher in the UK compared to the USA on Tuesday. The US death rate is still three times higher (per million), but cases have more than doubled so those rates may well be...

No matter how many times they say this, it is simply not true. It is so frustrating that they keep insisting on this nonsense.

Which conveniently eliminates the possibility to collect long term followup comparisons.

The biggest problem with studies like this is the assumption that patterns of glycolysis or mitochondrial respiration in PBMCs is somehow relevant, despite the fact that the microenvironment for PBMCs is quite different to other tissue types.

Yes, the UK trial of household transmission of healthcare workers showed that although the risk was reduced, some healthcare workers who were vaccinated still contracted the disease and likely infected household members. https://www.nejm.org/doi/full/10.1056/NEJMc2107717

Research utilising standardised outcomes DESIGNED BY patients may indeed advance the field by eliminating all of the treatments that don't work. 'patient research partners' doesn't mean ME patient. Here is the profile of one of those partners: https://sciprofiles.com/profile/1679339

Has anyone trialled a "give money to patients" study. Basically, whatever money they'd spend on therapists handed directly to patients? :D

I had similar symptoms from late March last year, my labyrinthitis took about 6 months to recover, I still have some ear blockage issues. It also infected my mouth, causing significant gum recession and I still have strange mouth/gum pain. I'm not sure this was due to COVID though.

Yet this is simply contradicted in the next paragraph: If it isn't physical, then what is it? It's so disappointing that the people who frequently mention how mind-body dualism is the problem and the reason why illnesses are not understood, are often dualists themselves.

I know someone with ME who suffered from encephalitis after a bacterial infection that came from the lab they worked in...

GBS is characterised by severe paresis/paralysis that starts in the extremities, typically the legs, though sometimes the arms. Occasionally there is a facial variant. Foot drop associated with GBS is never 'occasional', but continuous and takes months to recover from (if there is full...

A shorter-term study (median 6 year followup) https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1468-1331.2008.02311.x

https://pubmed.ncbi.nlm.nih.gov/22336700/ Notably, 47% of participants reported long term fatigue on the questionnaires. Unfortunately, this wasn't a true prospective study, nor did they use objective measures of functioning or fatigue. Anecdotally, some post-GBS patients do suffer from PEM...

The true believers in the "powerful placebo effect" have no problem with magical healing crystals, though some feel that mainstream medicine should have a monopoly over placebo effects (rather than complementary/alternative medicine).

Recovery of deleted deep sequencing data sheds more light on the early Wuhan SARS-CoV-2 epidemic https://www.biorxiv.org/content/10.1101/2021.06.18.449051v1