Karl Johan Tronstad, Øystein Fluge and Olav Mella have been awarded just short of €1Mio to investigate "Impaired microcirculation and tissue hypoxia as a possible mechanism in ME/CFS".
The project summary is:
"Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating...
Posts have been moved into this thread from the News in Scandinavia thread.
Forskningsrådet (The Research Council) has awarded the team at Haukeland 11 million NOK to their research on ME/CFS and energy metabolism :party::party::party:
11 millions awarded the project: Impaired microcirculation...
Long Covid – Into the Third Year
As the COVID-19 pandemic reaches the end of its third year, and as COVID-related mortality in North America wanes, long Covid and its disabling symptoms are attracting more attention. Some individuals report symptoms lasting more than 2 years, and a subset...
I also think they did well in not overestimating things, using good controls, excluding children with pre-existing pathologies, validated everything by two paediatricians and a third one in case of uncertainty. Furthermore outpatient visits, specialist visits and even antibiotic courses are...
The following classification was used.
Neurological: Focal deficits, Hearing loss, Seizures, Cognitive impairment, including attention deficits (ADHD), amnestic problems, learning disabilities in children, Visual impairment, Headache (migraine), Asthenia or Fatigue, Vertigo, Motor impairment...
Comparative study showed that children faced a 78% higher risk of new-onset conditions after they had COVID-19
Abstract
Aim
Children have largely been unaffected by severe COVID-19 compared to adults, but data suggest that they may have experienced new conditions after developing the disease...
They "found no significant difference in plasma levels of SARS-CoV-2 spike and nucleocapsid proteins in participants pre- compared to post-vaccination"
It seems there are also some different methods to determine whether the spike protein is vaccine induced or virally induced. It would be...
I can't tell if they really include recovered people, but if they don't that would essentially mean that every patient has at most 2 symptoms (with most patients only having fever as only symptom) which really isn't a lot and probably wouldn't be very different from controls. Add on top of that...
So they aren't able to replicate the findings of Hohberger and other groups https://www.s4me.info/threads/persistent-endothelial-dysfunction-in-post-covid-19-syndrome-and-its-associations-with-symptom-severity-and-chronic-inflammation-2023-kuchler-et-al.33504/#post-486399, but this might be due...
The author Manuel Ruiz-Pablos seems to have a general interest in EBV related diseases and published https://pubmed.ncbi.nlm.nih.gov/35894054/ and https://pubmed.ncbi.nlm.nih.gov/34867935/. He is also a patient that sufferes from ME/CFS https://twitter.com/manruipa.
Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID?
Abstract
Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...
Exploring the mechanisms of long COVID: Insights from computational analysis of SARS-CoV-2 gene expression and symptom associations
Abstract
Long coronavirus disease (COVID) has emerged as a global health issue, affecting a substantial number of people worldwide. However, the underlying...
Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death
Background
We have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during...
Cognitive impairments and mental health of patients with post-COVID-19: A cross-sectional study
Abstract
Background
Persistent cognitive complaints belong to the most frequent symptoms after COVID-19. This study explored the neuropsychological profile, mental healthand risk factors for...
One-fourth of COVID-19 patients have an impaired pulmonary function after 12 months of disease onset
Abstract
Background
There is increasing data that show a persistently impaired pulmonary function upon recovery after severe infection. Little is known however about the extent, recovery and...
Tweet by den Dunnen on this study and possible connection to LC www.twitter.com/DrDenDunnen/status/1701883106905493862 translated into English: “This is indeed specific drug candidate for severe acute COVID-19, which is very likely to have a different cause than Long-COVID. So this is not a...
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