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Thanks for sharing @Dolphin and lovely that medicalnewsbulletin covered this. The article opens with Is that really the case? Has anybody looked at muscle cells in particular in relation to post exertional malaise? From what I can tell Rob Wüsts exploratory, not yet published data, would...

Van Vugt told me in a conversation a couple of months ago that they applied for a new grant in a new government funding round so that they could continue their IDO2 work in LC. It is my interpretation that they meant these grants, because I'm not aware of any other funding (but it still means...

Thank you. Yes, that's what I meant.

That is something I don't know (I believe to know Wüst/van Vugt did), but I would be surprised if one of them hadn't, especially since their CBT study was "successful".

Most of the patients were hospitalised (17 out of 21) are also more than 10 years older than the control group on average and have a much higher BMI. I cannot see what the mean Long-Covid duration is, but they recruited patients 4–16 weeks after a COVID-19 infection, which seems far too early to...

Impact of long COVID on the heart rate variability at rest and during deep breathing maneuver Abstract While the majority of individuals with coronavirus disease 2019 (COVID-19) recover completely, a significant percentage experience persistent symptom, which has been characterized as Long...

Yes, on the other hand for the above paper, since it's a large majority of elderly males that have only been sick for a shorter time period (<6 months), I expect that the majority of them will probably have self-resolved fatigue as typical for many viral infections. Unless your goal is to...

This is a conference abstract. To the mods: Would it be possible to add "conference abstract" or something similar as tag? I've added this work since Maitland-van der Zee recently received a grant to do LC research in the Netherlands. Some of her other work includes Identification of long...

4 new grants for Long-Covid research have been announced https://www.zonmw.nl/nl/nieuws/start-post-covid-onderzoek-en-vooraankondiging-subsidieoproepen-onderzoeksprogramma-post. The 4 projects will be: Characterization of aberrant immune response in post-COVID using innovative STP technology...

Fatigue in post COVID-19 patients: the P4O2 COVID-19 study Abstract Background: Some patients do not fully recover after COVID-19 and have symptoms occurring 3 months after acute illness, lasting for >2 months, defined as post COVID-19. Fatigue seems most present in post COVID-19 and part of...

Thank you for providing some extra context (I certainly believe free access shouldn’t be a compliment, but a necessity). I’m suprised by how quickly all reviews came in for such a questionable paper (9 reviews already within 5 days) do you have some information on how the reviewers are chosen?

Don't think anything useful can be said about three case reports. I had never heard of the website/journal Qeios and the website seems very scammy (very ChatGPT-like) but at least some of the reviews on this paper do actually pose the right kind of questions (some also seem awfully strange)...

Profound Symptom Alleviation in Long-Covid Patients After PAMP-Immunotherapy: Three Case Reports Abstract Background Long-Covid patients suffer from a range of symptoms with a largely varying degree of severity, including chronic fatigue syndrome (CFS), myalgic encephalomyelitis (ME)...

Is there a meta-analysis on this somewhere that somehow tries to explain all different results? Personally, I feel like the results aren't consistent enough, possibly due to inconsistent methodology, varying cohorts or it not being quite as useful method as some patients believe, possibly...

Cohort characteristics: 277 Long-Covid patients, 50 healthy controls. Contrary to many other studies, this study did very well in terms of not only recruiting elderly people (mean ages LC=48, HC=48) and they also did well w.r.t. sex distribution in their cohorts (62% females in LC vs 64%...

What are you doing UK scientists? You can't just go and measure the heart rate of a patient. You're supposed to gaslight them!

The post-COVID-19 population has a high prevalence of cross-reactive antibodies to spikes from all Orthocoronavirinae genera ABSTRACT The Orthocoronavirinae subfamily is large comprising four highly divergent genera. Four seasonal coronaviruses were circulating in humans prior to the...

That must have been a bit of work! I thought the research by Rob Wüst's team interesting as well (finally someone looking at muscles and metabolites w.r.t. PEM!), even though the majority of it hasn’t been published yet (some of their work was published here and other parts have been discussed...

A letter to President Biden has been signed by Policy experts, scientists and disability groups. The subject is "Address the Crisis of Long COVID and Other Infection-Associated Chronic Conditions in FY25 Budget". The letter can be found here. It might be useful to remember these names for...

Same group that published People With Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Exhibit Similarly Impaired Vascular Function, 2023, McLaughlin+. I don't have access to this paper, but their previous paper didn't mention which diagnostic criteria were being...