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    BBC Article : Why Covid is still flooring some people

    It’s never about risks being cumulative (especially not with the LC definition that is being used), that’s just a trivial fact that would apply to any viral infection (in fact it applies to any health adverse event and it even applies to non-health adverse events as it applies to simply time...
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    Risk of Multiple Sclerosis in People Living with HIV: An International Cohort Study, 2023, McKAy et al

    Risk of Multiple Sclerosis in People Living with HIV: An International Cohort Study Abstract Objective There has been interest in a possible negative association between HIV and multiple sclerosis (MS). We aimed to compare the risk of MS in a cohort of individuals living with HIV to that in...
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    £622,000 grant to improve diagnosis and treatment for ME/CFS and Long Covid

    In Germany there's also a large study called BOSCO which is generally looking at all outcomes to Covid. I can't see whether their classification of Long-Covid is useful enough to reveal anything about Long-Covid, but they at least are looking at it (translated from homepage) "The extent to which...
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    Long-term outcomes following hospital admission for COVID-19 versus seasonal influenza: a cohort study, 2023, Xie, Al-Aly et al.

    I don't think anybody should be suprised that any health disruption happening to 70 year old males with several comorbidities can bare health consequences. I strongly doubt you'll find any useful answers there though or that it's even anything worth studying in the fashion it's done here...
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    The Observer/Guardian article: Does the microbiome hold the key to chronic fatigue? About patient led 'research' group Remission Biome.

    Dr.T. : "Important note to my followers and the @remissionbiome community: I am no longer associated with @remissionbiome or Renegade Research. I owe you all an explanation and one will be forthcoming once I have been given the legal go ahead. My mission remains the same as it has always been...
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    News from Germany

    ME/CFS Research Foundation on Twitter www.twitter.com/MECFSResearch "In 2024, a #MECFS research project will start at ChariteBerlin, which we are jointly funding with the @LostVoicesStiftung. Focus: researching biomarkers and disease mechanisms using an advanced blood analysis method." Details...
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    USA: The RECOVER Initiative - Long Covid research

    200 million, now that's proper budget with which you can do a tremendous amount of exercise and lifestyle intervention studies.
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    Thesis Eccentrically Induced Skeletal Muscle Damage in Patients With Chronic Fatigue Syndrome CFS, With Reference to Overtrained Athletes, 1995, Wright

    Great find, could be valuable if someone shared this with the team of Rob Wüst, perhaps they haven't seen it either.
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    FTY720 requires vitamin B12-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis, 2023, Kihara et al

    FTY720 requires vitamin B12-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis Highlights CD320 expression is suppressed in MS and EAE astrocytes S1P1 inhibition upregulates CD320 expression in astrocytes Fingolimod and sphingosine directly bind to...
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    Dementia and mortality in older adults: A twin study, 2023, Jung Yun Jang et al

    Dementia and mortality in older adults: A twin study Highlights We studied dementia and mortality in twin pairs discordant for dementia. People without dementia outlived people with dementia. Identical twins with dementia and their co-twin controls had similar survival time. Findings suggest...
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    In vitro B cell experiments explore the role of CD24, CD38 and energy metabolism in ME/CFS, 2023, Armstrong et al

    In vitro B cell experiments explore the role of CD24, CD38 and energy metabolism in ME/CFS Disturbances of energy metabolism contribute to clinical manifestations of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Previously we found that B cells from ME/CFS patients have...
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    CDC Data Brief: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in Adults: United States, 2021–2022, 2023, Vahratian, Unger et al

    It seems to me that it would be fairly easy and useful to do some statistically significant sampling of health records within the CDC study or a similar one (sampling a subset of the patients in the survey to have doctors appointments would also be great, but probably too much effort). The...
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    Mechanisms underlying exercise intolerance in Long COVID: an accumulation of multi-system dysfunction, 2023, Jamieson et al

    Cohort characteristics: Matching isn't perfect with LC patients having quite a few pre-existing conditions (as they mention in the limitations section these pre-existing health conditions make it harder to draw conclusions): They used NIRS, previously discussed here They also mention that...
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    Mechanisms underlying exercise intolerance in Long COVID: an accumulation of multi-system dysfunction, 2023, Jamieson et al

    Now published - final abstract here Preprint Mechanisms underlying exercise intolerance in Long COVID: an accumulation of multi-system dysfunction The pathogenesis of exercise intolerance and persistent fatigue which can follow an infection with the SARS-CoV-2 virus ('Long COVID') is not fully...
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    Post-COVID exercise intolerance ...associated ... capillary alterations and immune dysregulations in skeletal muscles, 2023, Aschman, Scheibenbogen +

    Now published as Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles.
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    Demystifying Long COVID International Conference Dec 2023

    Demystifying Long COVID International Conference 2023 | Day 3 www.youtube.com/watch?v=AP3qHM3Acz4 Program "A Patient Perspective" Chantal Britt Pauline Oustric "A Perspective from a Family Doctor" - Gemma Torrell "A Two-Sided Coin: A Clinician and a Patient Perspective" - Annemarie...
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    Blood transcriptomics reveal persistent SARS-CoV-2 RNA and candidate biomarkers in Long COVID patients, 2024, Menezes et al.

    A recording of the talk, as well as of every other talk can also be found on YouTube www.youtube.com/watch?v=gEsjR2y6fzs. When such "phenomenal" and very interesting preliminary results, which do significantly differ from previous results, are presented by a new team from a "smaller" lab I find...
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    CDC Data Brief: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in Adults: United States, 2021–2022, 2023, Vahratian, Unger et al

    Not necessarily. It's also explainable by ME/CFS patients having a lower live expectancy than healthy people. I believe there is sufficient evidence and reasoning to make such a claim, albeit ME/CFS not being a directly deadly disease (lower income, less accessibility to health care and...
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    Experiences of Canadians with long-term symptoms following COVID-19, 2023, Kuang et al

    Overview of the study Using data from the 2023 Canadian COVID-19 Antibody and Health Survey – Follow-up questionnaire (CCAHS- FQ),1 this article provides updated estimates on COVID-19 infections and reinfections among Canadian adults, and describes the nature of symptoms experienced as a result...
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    Implications of the quality of the doctor-patient relationship on health in adult ME/CFS patients... 2023 Habermann-Horstmeier & Horstmeier

    This link should work (only the first part of the above link appears to be broken): https://link.springer.com/article/10.1007/s15006-023-2894-z.
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