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  1. Kitty

    Amitriptyline Downregulates Chronic Inflammatory Response to Biomaterial in Mice, 2020, Scheuermann et al

    I think it's often just that they've tried it and found that it did nothing, or made them worse. Personally, the tricyclics I've tried (including amitriptyline at everything from 5mg to 30mg) caused significant depersonalisation, which led to feelings of depression. I never got past that stage...
  2. Kitty

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    The article above appears to have been translated through half a dozen languages before arriving at the English! :rofl: ...He added: “It’s not a title-tattle, it’s a baldardash and nonsense. I can tell you I’m less than a few butcher dogs."... ...Furthermore, young people tend to report taller...
  3. Kitty

    Coronavirus - worldwide spread and control

    Indeed. Instead, it's full of tin-hat conspiracy theories. Perhaps if we didn't have leaders whose actions and decision-making have left the satirists struggling for material, the rest of us might be able to behave more rationally...
  4. Kitty

    Coronavirus - worldwide spread and control

    Similar thing has happened where I live. Number of cases in my local area stands, as it has done for months, at 0 - 3 per week in a population of about 7,500. In one of the student areas, they're at 750+ per week within a similar-sized population. Some students* are refusing to stay in and...
  5. Kitty

    WHO Disability Assessment Schedule 2.0 (WHODAS 2.0)

    Absolutely. You'd have to repeat it every day for months in order to get a broad historic average, but as that wouldn't describe your status accurately for most of the time – and would be subject to change anyway – it's probably a waste of energy.
  6. Kitty

    DecodeME - UK ME/CFS DNA study underway

    Just for info, several local groups that I belong to have trouble with BT internet addresses – it seems to be a particular issue with mailing lists.
  7. Kitty

    Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress..., 2020, Wang et al

    I'm not sure it does? It seems to suggest that raised levels of circulating MMA may be an indicator of mitochondrial dysfunction, and that this dysfunction could be prognostic for increased mortality. Furthermore, the increased mortality risk is still present even when participants do not have...
  8. Kitty

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    The BBC does frequently mention them in items about various aspects of medicine, especially on R4 and News 24, so it wouldn't be in the least surprising.
  9. Kitty

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    :laugh::laugh: Well, as long as the volte-face is complete, and includes ME and other patients with 'unexplained' fatigue, I for one won't complain. We need to find a way to move this whole thing forward now – we can argue about the history later.
  10. Kitty

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    From today's Grauniad – apologies if it's already been posted, I couldn't spot it: Long Covid: the evidence of lingering heart damage https://www.theguardian.com/world/2020/oct/04/long-covid-the-evidence-of-lingering-heart-damage
  11. Kitty

    DecodeME - UK ME/CFS DNA study underway

    Have emailed you, @Andy.
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