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Fort Detrick jumps out, of Eight Ball infamy. What with Wuhan Labs, the irony is a slap in the face.

I've read that version as well. Speaking of depressing, using the word "proven" in a Lyme context is dicey usually even in the most stalwart studies. It shouldn't be that way after half a century.

"There's "no evidence " debilitating but common symptoms she's had for 15 years are driven by Lyme." Well, technically not correct, if I'm reading the article right. She did test positive for Lyme, which is a form of evidence (can you imagine if she'd tested negative what people would say if...

Yes. But as is frequently the case with ME/CFS, things can get complicated very quickly in Lymeworld. First, when I talked about a vaccine wagging the Lyme dog, I was referring to reports that diagnoses of chronicity with Lyme might interfere with getting vaccines approved. As I understand it...

Frequently, it's living with tick-borne diseaseS. It's rapidly become a package deal. As for whether or not a Lyme infection is actually gone, there is literally no way to know. None. An embarrassing failure. You also have to deal with more prevalent incidence of failed treatment when not...

If pathogens are involved, certainly if they persist and are causal, then that becomes the playing field, and identifying them is essential. Diagnostics need to re-invent their industry, or at least recalibrate it. Like most of medicine, diagnostics need an overhaul. And researchers cannot...

Grim article. Smacks of catastrophizing to me. Does BMJ keep an open mind about balance pieces? Something like"Top Ten Reason Some Are Whining About The Nice Guidelines"?

I wonder how doctors' evaluations might change over years if the patient morphs from one with typical issues to one with chronic issues that the clinician cannot help.

I test positive for babs, and babs purportedly can impact platelet counts, and my platelet count is usually low. I bruise easily and frequently. Some bruises I've had for years. This is a relatively new issue for me. So is testing babs-positive ( a few years). But that's me. So Babs aside, I'd...

On paper, an NIH division dedicated to examining chronic infectious disease sounds appealing. Apparently it has the support of several people who have my support, e.g., Lorraine Johnson and Dorothy Leland. The whole safety in numbers thing resonates with me, for sure. I'm curious as to how the...

Who said anything about inventing anything? I fail to see how "conspiracy" hasn't devolved into a sad and twisted cliche any more than EBM. Again, I'd let the discussions carry themselves where they will. It's a forum. Once we pre-emptively begin deciding what is truth or not, I fear it...

Aren't many of us forum members in some way conspiracists? And EBM hasn't always been good to us, or reliable. I think that's where the merits of discussion come in.

I'm not sure why on a gut level I find this position worrisome, but I do.

As I think you know, channelopathies might qualify.

My n=1 tale is sleep doesn't help, even a good sleep doesn't help, but a bad sleep, i.e., worse than typical, can make things decidedly worse.

BTW, one of the reasons I think DecodeME has merit is the seeming relevance of the 80/20 rule in both Long Covid and Lyme. Is there a significant minority of the population that find it more difficult to clear pathogens due to genetics?

I'm sorry, I'm not following you. What theory? Lyme is tissue-tropic. That's not a theory. PCR tests for agents - or their remnants' - DNA, hence it's a direct test of sorts. It's typically employed in serum draws, so the DNA needs to be in the blood. None of that is theory. It may be helpful...

But it doesn't, much in the same way that saying we cannot find the spirochete in direct testing in most cases after the bull's-eye doesn't. PCR is a direct test, usually used in blood serology, and Bb flees blood first chance it gets. I don't believe that for a nano-second. This appears to be...

Not necessarily. Look at the NIH's definition of genetic predisposition: https://www.cancer.gov/publications/dictionaries/genetics-dictionary/def/genetic-predisposition Whenever lifestyle emerges as a supposed factor, the cork is out of the bottle. Not trying to be negative, just looking at...

Human nature. Agreed. Nor do they over the pathogen by which they are infected. Perhaps it's just a pick your own poison. If I were directing monies I'd prioritize new and better diagnostics for herpes variants and enteroviruses and tick-borne diseases, etc. Or the opposite could happen if no...