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  1. Peter T

    Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with ME/CFS, 2021, Rowe et al

    What don’t yet know is if Long Covid results in an assortment of cooccurring problems including ME/CFS, that is the original virus triggers conditions/symptoms only indirectly related to each other such as specific neurological damage or lung damage, which for some also includes the condition...
  2. Peter T

    Open Effectiveness of Acceptance Commitment Therapy or Micro Breaks in Patients With Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis

    You do make the important point @Snowdrop that research so poorly designed that it is never going to produce any meaningfully interpretable results can never be cost effective in terms of science or medicine, despite many researchers and clinicians building their careers on the back of it. What...
  3. Peter T

    Hair cortisol levels in women with medically unexplained symptoms (2021) Fischer et al

    Thank you for the link. I saw ‘pre print’ and just assumed the full article was not yet published. This is what they say in terms of aetiology: This is what they say about patient selection: So those those in the functional somatic syndrome group had a number of distinct disorders lumped...
  4. Peter T

    Hair cortisol levels in women with medically unexplained symptoms (2021) Fischer et al

    Do we know if cortisol levels relate differentially to physical stress and psychological stress? A health condition, regardless of its aetiology, may be a source of psychological stress but it may also be a cause of physical or biological stress.
  5. Peter T

    Hair cortisol levels in women with medically unexplained symptoms (2021) Fischer et al

    I am not sure I understand the difference between their two ‘functional’ groups: As the article is not yet available we don’t yet know any more about how people were allocated to each group, whether this was based on questionnaires or clinical judgement. Given there is no positive evidence...
  6. Peter T

    WHO: A clinical case definition of post COVID-19 condition by a Delphi consensus

    Suggestions for change in the final version could come from the Lancet editorial team, from peer reviewers or be made by the authors themselves.
  7. Peter T

    Covid-19 vaccination experiences

    I don’t think all the others were from New York, so unlikely that they would all have had a booster on the same day or the same place as my niece. Where there is high levels of the virus, even if people take lateral flow tests, there is going to be a number of people getting the booster who...
  8. Peter T

    Covid-19 vaccination experiences

    Interestingly, after my Moderna booster I had a very bad couple of days with lots of aches and pains and some lung issues, which resolved fairly quickly. However I have slept a lot more than usual in the following two weeks, which has mostly been a positive as I have largely been sleeping...
  9. Peter T

    Covid-19 vaccination experiences

    Here in the UK I am aware of several individuals classified in the highest at risk grouping as having been offered a fourth injection, though it seems as something coming soon rather than something to book for next week. The two I know best (one with a lung condition and the other with type 1...
  10. Peter T

    Exploring the Preference for Fatigue-avoidance Goals as a Mediator Between Pain Catastrophizing, Functional Impairment and.., 2021, Velasco et al

    Is it in any way possible in this context to distinguish between ‘pain catastrophizing’ and accurate insight into your body’s pain responses?
  11. Peter T

    Review article: Physical and psychological comorbidities associated with irritable bowel syndrome, 2021, Shiha and Aziz

    My IBS has resolved over the years into a clear predictable pattern: episodes are triggered by specific foodstuffs, either high sugar content or foods that I am specifically intolerant to, being a day or so into an episode of PEM or in the later stages of a migraine where the pain is severe...
  12. Peter T

    Covid-19 vaccination experiences

    There must be a margin of error. My niece in New York recently tested positive for Covid two days after having the booster. She was having lateral flow tests every few days, and met with some friends (all twice vaccinated/tested negative) over the weekend before last, then two days later she...
  13. Peter T

    Aphaeresis/ Apheresis (for removal of microclots)

    Isn’t describing this as a ‘pioneering treatment’ rather than an ‘experimental intervention’ rather prejudging the issue? Someone had what they thought was a good idea and then rather than evaluating it experimentally set out to make money from it.
  14. Peter T

    ME Aware Surgical Teams UK?

    Would it also be worth setting out what we need a surgical team to be aware of? Including: best anaesthetic? possibility of adverse drug reactions hypersensitivities PEM risk of triggering deterioration in underlying ME? longer recovery periods needed?
  15. Peter T

    What treatments work for anxiety and depression in children and adolescents with [CFS]? An updated systematic review, 2021, Clery et al

    Though not everyone with ME has a vitamin B12 deficiency, there is the suggestion that a B12 deficiency is more common in people with ME compared to the general population. However there are a number of possible explanations for this hypothetical association It is an indirect result of ME, eg...
  16. Peter T

    The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS

    So you have some researchers attempting to study ME and/or fibromyalgia in mice where it is impossible to use questionnaires and other researchers studying the same conditions insisting that they can only be studied by subjective self reporting through questionnaires. Am I missing something here?
  17. Peter T

    Split-Second Unlearning: Developing a Theory of Psychophysiological Dis-ease, 2021, Hudson and Johnson

    Are these pins with psychophysiological stress lurking beneath them, the same ones that have an undetermined number of angles dancing on their head? Both are about equally measurable and equally available to scientific verification.
  18. Peter T

    Chronic Fatigue Syndrome and Occupational Status: A Retrospective Longitudinal Study, 2021, Chalder et al

    Very useful letter by @Brian Hughes and @dave30th, it will be interesting to see if the editorial team at Occupational Medicine are as practiced at brushing off or ignoring coherent on point criticism of articles that their peer review system should have pulled as the usual suspects.
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