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  1. Cheshire

    Documentary on James Watson (on scientific advisory board of OMF)

    Definitively not a nice guy: https://liorpachter.wordpress.com/2018/05/18/james-watson-in-his-own-words/ (Warning, it's really not pretty) Edit: and scientifically questionable (eg: “There is a biochemical link between exposure to sunlight and sexual urges.. that’s why you have Latin lovers”)...
  2. Cheshire

    A general thread on the PACE trial!

    Yes, I've never understood this blatant contradiction: patients are told that focusing on symptoms is a factor in perpetuating them. Yet the first thing you're ordered to do in a CBT course is to keep a diary of your symptoms which makes you focus on them. (I guess it's the same logic as in the...
  3. Cheshire

    The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect? (2018) Molendijk et al.

    Open access here. Many similarities with the PACE flaws:
  4. Cheshire

    'Widespread and dangerous': Facing medical uncertainty, some doctors tell patients it's all in their heads CNN

    https://edition.cnn.com/2018/12/21/health/medical-uncertainty-diagnosis-afm/index.html
  5. Cheshire

    Metabolic fingerprinting for diagnosis of fibromyalgia and other rheumatologic disorders (2018) Hackshaw et al.

    (Paragraph breaks are mine) Open access: http://www.jbc.org/content/early/2018/12/06/jbc.RA118.005816.long
  6. Cheshire

    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    They really managed to get an impressive press coverage, more articles in French: https://www.pourquoidocteur.fr/Articles/Question-d-actu/27761-Syndrome-fatigue-chronique-viendrait-de-systeme-immunitaire...
  7. Cheshire

    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    I would have bet that a few months ago, but given how discredited the PACE trial is, I'm not sure it is tenable, and even they are starting to realise it. But at the same time, they've shot themselves in the foot so often, so they may try...
  8. Cheshire

    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    Or maybe a sign that he is starting to sing a different tune (I realise that this is probably way too optimistic, but, hey, who knows?)
  9. Cheshire

    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    In The Conversation, "Chronic fatigue syndrome: new evidence of biological causes"
  10. Cheshire

    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    FWIW, two short articles in French: https://www.topsante.com/medecine/fatigue/fibromyalgie/la-fatigue-chronique-un-probleme-immunitaire-629678 https://www.numerama.com/sciences/448745-vous-etes-tout-le-temps-fatigues-cest-peut-etre-la-faute-de-votre-systeme-immunitaire.html
  11. Cheshire

    Parachute use to prevent death and major trauma when jumping from aircraft : randomized controlled trial

    Yep Is it a tradition, like April fool's day or is it an innovation on the part of the BMJ?
  12. Cheshire

    NICE guidelines update

    NICE documentation NICE guidelines 2007: Link to document 2007 NICE guidelines setup: General comments from stakeholders (CFS/ME consultation draft 29 September – 24 November 2006) Link to document 2018-2020 NICE guidelines revision: Final scope Link to document Consultation on draft scope...
  13. Cheshire

    Patients’ hopes for recovery from myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS): Toward a ‘recovery in’ framework. (2018) Jason

    Devendorf, A. R., Brown, A. A., & Jason, L. A. Chronic Illness Paywall https://journals.sagepub.com/doi/10.1177/1742395318815965
  14. Cheshire

    ME/CFS services in the United Kingdom

    The way the second sentence is worded is so problematic... It implies that you are either pathologically devoted to others or lying. Tails we win, heads you lose. Apart from being deshonest, and patronising, it is also revealing about their hubris. They can't be wrong. They can't imagine...
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