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Moving right along in our data mining operation... CDC Wonder is a website which provides access to several interesting public health datasets. I downloaded age-standardized rates of causes of death grouped by state from the Multiple Cause of Death 1999 - 2020 dataset. This dataset gives the...

One slightly frustrating thing about Google Trends is that the data does not appear to be consistent if downloaded on different days, even if representing the same time span and search term. The 22 year data for ME/CFS I was using was downloaded on 2026-03-24, and represents the time span of...

The paragraph above is referring to the top left plot. Seems like it could be interesting, but the p-value isn't very low, and from the plot it looks like there were only two people in the mild group and two people in the severe group for this test. The other three plots were based on a more...

I again ask that you provide the reason you think that T reported by 23andME or any other company would mean translation into valine, because this doesn't seem to make sense. There is no thymine (T) molecule at this location in the DNA on either strand if valine is included in the protein...

Technically, for Metformin, the use they're recommending is for preventing long COVID before it starts, not for symptom reduction in already sick people.

Could you please copy the specific information in the sequencing results which says TT is present at this location, and the documentation from the sequencing company that this interpretation is based on? I don't know why any sequencing company would report a T in this location for someone with...

Human Endogenous Retroviruses and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Emerging Insights into Their Role in Disease Pathogenesis, Immune Dysregulation, and as Potential Biomarkers and Therapeutic Targets Perera, Krishani Dinali; Garcia, Elisa Oltra; Carding, Simon R. Abstract...

I think whoever wrote the abstract skipped their correlation does not equal causation class.

Associations of physical fitness and choice reaction time with chronic fatigue in working-age adults: a population-based study Background Chronic fatigue is prevalent among working-age adults and has been linked to reduced physical capacity and impaired cognitive performance. While...

Yeah, it looks to be higher than in the US: Scottish Canadians Scottish Americans Also higher when considering the more general British ancestry: British Canadians British Americans If British ancestry were a risk factor for ME/CFS, then presumably we'd see a larger prevalence in...

A new version was posted that no longer includes Amy Proal or Michael B. VanElzakker as authors.

Elevated blood viscosity is associated with dysautonomia in long COVID symptoms Background Long COVID is associated with elevated inflammatory and antibody levels. Elevated plasma proteins can increase blood viscosity and decrease blood flow. Our aim is to evaluate if blood viscosity is...

They also published: Summary for Patients: Fluvoxamine and Metformin for Fatigue in Patients With Long COVID Web | DOI | PDF | Annals of Internal Medicine

Yes, on Google Trends, you can pick Metro or City for the subregion option. Metro does make it more fine-grained into 210 areas, but the problem is that it becomes a lot harder to try to correlate it with other variables, since I think it'd be hard to find various stats like average income or...

The geographic clustering is very distinct for ME/CFS searches. Here's a map for proportion of each state reporting Scottish ancestry calculated from the B04006 census dataset. It's also clearly highest in the same two general regions:

It's kind of difficult to see the actual pattern among states on the Google Trends map for ME/CFS, so I made a map with much more contrast. The two upper corners of the country seem to have the highest scores for ME/CFS searches.

Camisado highlighted the band Moodring in another thread: News article on the website Metal Injection: HUNTER YOUNG of MOODRING: "When I Get That Low, I'm Like, ‘Oh F*ck, What If I Don't Come Out Of This?’ Because Some People Don't.” Link

I like it! Lyrics:

Exploring duplication in reviews of Long COVID: 2020-2023 Gary Austin Raine; Claire Loise Khouja Background The unnecessary duplication of reviews is a recognised problem in the field of evidence synthesis. This paper reports findings from a study exploring potential duplication of effort in...