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Why does FND mainly affect women? A consideration of gender imbalance in neuropsychiatric disease [Line breaks added] Background Functional neurological disorder (FND) is a common and disabling neuropsychiatric condition in which women comprise approximately 75% of cases. This paper...

Pathophysiological mechanisms of post-exertional malaise: an integrative analysis based on the metabolism-immune-neuro interaction model Abstract Post-exertional malaise (PEM) is a common core symptom in various chronic debilitating conditions, such as Post COVID-19 Condition (PCC, also known...

There seem to be a few main possibilities that all seem plausible: People with British or Irish ancestry have a higher genetic predisposition to ME/CFS. States with higher British or Irish ancestry have higher levels of an environmental risk factor for ME/CFS (e.g. infections). People with...

I was talking about the British - ME/CFS correlation with my brother, and he said something like "aren't those basically the states that have the most white people?" and suggested that it could be basically how white people may get diagnosed at different rates from other races due to cultural...

Should we be thinking more about migraines? Autoimmune disease is often discussed as also having a similar sex bias to ME/CFS. But migraine fits that picture as well, and does not really seem to be in the same category as autoimmunity. The large scale correlation search with other trends scores...

Association of ADIPOQ rs1501299 with long-COVID syndrome: a single-center cross-sectional study Background Long-COVID syndrome is a public health issue, affecting millions of individuals worldwide. However, the pathophysiological mechanisms underlying the syndrome’s sequelae are still under...

3D Virtual Reality Performance Metrics as a Future Fatigue Biomarker in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disorder, characterized by symptoms such as post-exertional malaise...

Some posts have been moved to: A thread of no importance. Post something completely inconsequential.

What exactly are you basing T/A coding for valine on? Edit: You previously said the opposite for A and G. Why has that changed?

Yes, it looks comparable. The Post-exertional malaise topic (capitalized above) has a large correlation, but who knows what terms this encompasses. The specific term "post exertional malaise" is lower, but still high. Honestly, the idea about the correlation of ME/CFS searches with British...

Thanks! I should have done a quick search because just seeing the search results for "west virginia unhealthy" makes it very clear this probably is actually related to their health. I thought it might be an issue with Google Trends, but I guess instead this provides more support about Trends...

Something weird seems to be going on with West Virginia (WV). I keep seeing WV listed as the number one ranked state by search interest, or at least highly ranked, for various diseases. To examine this more systematically, I downloaded the Google Trends state scores for the 28 common conditions...

I tested the above suggestions, alongside ME/CFS, "tired", "always tired", and "fatigue" as well, for English, Scottish, and Irish ancestry. I sorted by Pearson, but also tested Spearman to see if large outliers are masking an association (which seems to be the case for Mississippi being an...

Relatively low correlations of Scottish or English ancestry with these four search terms: Note that the data for "type 1 narcolepsy" and "type 2 narcolepsy" might not be very reliable, because there looks to be very little search volume for these, and unlike most searches, states only have...

The correlation of English ancestry with early onset arthritis in Murph's Australia census analysis, and the many diseases highly correlated to ME/CFS in my USA Google Trends analysis made me wonder if places with British people have higher rates of many diseases, whether through genetic or...

An imaging flow cytometry method to study platelet-monocyte aggregates using Long COVID as a model Background Long COVID is characterised by persistent systemic inflammation and endothelial dysfunction, with increasing evidence implicating thromboinflammatory mechanisms. Platelet-monocyte...

I managed to do this, using gtrendsR, as suggested by Murph. I decided to have an AI code basically the whole script, and I am pleasantly surprised by how well it works. Essentially, the script is testing how well search interest in "chronic fatigue syndrome" correlates to search interest for...

Yeah, mine has always said "Disability". In a video about Trends, they seem to imply that any word under the term other than "Search term" means a Topic. Interesting that your R2 is higher. Just to clarify, the trends page you're using says "CFS/ME" and not "Myalgic encephalomyelitis/chronic...

That's funny. I had to look it up: - https://en.wikipedia.org/wiki/Irn-Bru

A hypothesis connecting dysgeusia due to defects in ATP-P2X3 signaling and fatigue in myalgic encephalomyelitis/chronic fatigue syndrome: lessons learned from long-COVID Srinivasan, Mythily; Joseph, Paule Valery Abstract Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is a...