From the sensitivty analysis paragraph:
Is this saying an ME/CFS group was created which excluded only those 7 conditions, and compared that group to C2? So could the ME/CFS group still have included individuals with type 2 diabetes or other conditions?
I guess the concern could be put simply...
I recently was interested in migraine because I found a large correlation using Google Trends scores, showing that [edit: US] states that search more for "chronic fatigue syndrome" tend to also search more for "migraine" and "migraine aura".
I previously also did genetic correlations using...
I'm wondering about the specific points Hutan raised that don't seem to have been addressed yet. Is this study concluding that lipids are a problem in ME/CFS based on comparing an ME/CFS group that could potentially include individuals with multiple comorbidities to groups where individuals...
Insights into Pathophysiological Pathways in ME/CFS Through Genetic Correlation and Mendelian Randomization
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-acute infection syndromes (PAIS) are multisystem disorders involving immune, vascular, neuroinflammatory...
You can copy the website URL into https://translate.google.com/?sl=auto&tl=en&op=websites and it'll translate the whole page. Or just copy bits of text to translate.
If you use Firefox browser, it also has built-in translation, explained here...
Risk of Post-acute Symptoms and Conditions After SARS-CoV-2 Compared to Other Respiratory Viral Infections: A Systematic Review and Meta-Analysis
Background
How post-COVID-19 condition (PCC) differs from post-acute infection syndromes (PAIS) caused by other respiratory viruses remains...
Comprehensive Immunophenotyping of Monocytes and Dendritic Cells Suggests Distinct Pathophysiology in Chronic Fatigue Syndrome and Long COVID
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are complex chronic conditions that often follow infectious...
Corrigendum to ‘Effects of therapeutic interventions on long COVID: a meta-analysis of randomized controlled trials’
[Line breaks added]
Description of the error and impact on results and conclusion
After the publication of this article, a post-publication review revealed that, due to an...
Effects of Exercise-Based Pulmonary Rehabilitation in Patients with Long COVID: A Systematic Review and Meta-Analysis
Background/Objective
A substantial proportion of infected individuals develop persistent symptoms after the acute phase of COVID-19, regardless of initial disease severity...
Press Release: "Stealth Adapted Viruses Contributing to the Increasing Incidence of Colon Cancers: An Urgent Call for Extended Viral Studies"
Snippets:
Shear Stress Tolerance Threshold, eNOS Uncoupling, and the Two-Threshold Model of Post-Exertional Malaise in Long COVID: A Mechanistic Hypothesis with Implications for Physiotherapy Practice
Karipidis, Yiannis K.; Karipidis, Konstantinos Y.
Background
A subset of Long COVID patients presents...
Cardiopulmonary Exercise Test Results Do Not Change Over Two Sequential Days in Patients with Chronic Fatigue Syndrome
Background
Two consecutive cardiopulmonary exercise tests (CPETs) performed 24 hours apart is increasingly used to determine post-exertional malaise (PEM) and disability in...
Yeah, they put the statistics about Hispanic characteristics in other tables. B03001 has the number of Hispanic people in each state, as well as specific countries of origin. I hadn't realized that other table was there, so thanks for bringing this up.
Just looking at these maps of median housing age in US states or counties, it doesn't seem to match up well with the map of ME/CFS searches:
ME/CFS search interest:
Is there a better variable for the old house hypothesis?
And please keep the ideas coming, whether or not they're fully baked.
Aminopeptides ameliorate long COVID symptoms in immunocompromised rheumatic patients through immune reconstitution
Objective
To evaluate the effects of aminopeptide nutritional support on immune reconstitution and antiviral capacity in immunocompromised patients with rheumatic diseases...
I think maybe your research work is trying to do something different. If it's something like identifying what gene transcripts are important, and two genes are highly correlated due to being part of the same pathway, then it makes sense to just try to identify a single marker of that pathway...
Just visually looking at fitted values vs residuals, with a univariate model for each of the four variables, it doesn't look like any huge departures from linearity. Some outliers that might be skewing the slope.
Maybe not the cleanest line for Welsh. Here's the raw Welsh proportion plotted...
For migraine, the very high correlation I saw with "chronic fatigue syndrome" was with the search term "migraine aura". "Migraine symptoms" is also high, just not as high.
In terms of sex bias, Wikipedia says that migraine without aura is where there is a significantly larger risk in females...
One thing I was thinking about is that all the British and Irish ancestries probably tend to be in the same states, so, for example, is Welsh correlated with ME/CFS searches just because Scottish is, with the same states having high populations of both?
I tried doing a regression with all of...
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