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Again, I doubt this. For some reason being overweight is a massive risk factor for dying with Covid-19, even moderately overweight. It is possible that diabetes is not a risk over and above the strong link to being overweight but the additional link to Asian and African ethnicity suggests to me...

This may not be very well thought through. I would certainly expert someone with moderate to severe MS to be very much more at risk of pulmonary complications because of immobility and postural effects on the lungs. You might argue something similar for ME but I don't think it quite the same...

Epilepsy will be included for the specific reason that high fever induces fits - most specifically in children but I think also in general. It is a direct physiological effect of fever.

You may be right. The trauma of a PWME getting Covid-19 may be severe, whatever the path. Perhaps the specific mistake in the petition is to argue that ME should be on the list because it is a chronic neurological condition. That puts everyone of the track of common sense. If there is a vlid...

I think this is a mistake. I don't know of any theoretical reason to classify PWME as vulnerable for Covid or any clinical evidence that they are. Maybe there is evidence but does anyone know of it? Just being a chronic neurological illness is not a reason to be included. Sciatica is a chronic...

His name has been coming up for a year or so. It is not clear to me quite what his track record is. Maybe he has contacts n the BMA.

that some spend a huge amount of energy trying to dismiss It hardly required any energy at all once one had read the paper And it has been dismissed.

My wife points out that with the hand-held stick hoovers from John Lewis you can just do a minutes hoovering in one room and stand it back up against the wall in a cupboard. Now that we have it both of us more or less every day do a room that needs it almost without thinking. You are not put off...

We find it much easier than a canister one that rolls on the floor. Remember that if you are having to bend down and pick up a canister or lift it over a carpet a bit or bend to free a flex from a chair you are likely to be lifting up and down about 20Kg of your own body weight. The effort is...

I see from Ramsay's pages that what I have been calling PVFS is what he would call post viral fatigue states - which equates to what I think is the most common usage by UK physicians which is simply 'post-viral fatigue'. The designation of a PVFS syndrome to cover ME looks like a confusion, as...

That sounds like an incompetent opinion. A frozen state that looks superficially like catatonia occurs in people who are deliberately faking signs - I am not sure what you call them, maybe hypochondriacs or manipulative personality disorders. Maybe it can occur in people who get classified as...

It might if something interpretable was found. The first step is to find something consistent that is interpretable.

Based on my lab experience I suspect that the factors that prevent recovery are the same old factors that generated the problem in the first place - just not going away. But there are certainly various options. I agree that there are shades of grey but I think the pattern may be distinctly...

That is exactly what I meant by teleology. I have found the way to understand disease is to forget all about 'why?' and focus on what or how.

We have just got a 2 point something Kg John Lewis carry around hoover (not the cheapest which is heavier). It seems pretty good. The whole mechanism is up by the handle but if you going to lift it that is the best place because you don't have a moment of inertia to cope with. Moment of inertia...

Back in the 1960s various 'types' of clinical course of polio were described but I am not sure they are still considered valid. Most polio infections resolve with no long term illness at all. A small minority have paralysis. Recurrent polio infection is I think almost unheard of.

Very much the same discussion occurs with RA. I think a problem is that if we assume preconceived 'processes' like 'the recovery process' that might not complete we are in a sense putting a teleological or anthropomorphic slant on just some biochemical dynamics. Once we start dealing with...

It seems we are getting confused. Polio IS a viral infection. It has sequelae in terms of paralysis. I don't think the long term sequelae would be said to have a viral onset, although I suppose you could say that. Polio is not referred to as PVFS because it is not a fatiguing illness. It is a...

I think polio is something completely different. The long term situation is simply muscle paralysis due to anterior horn cell death. It is not related to any sort of fatiguing or ME-type illness any more than stroke or MS is.

I think this is an important question and I am not sure that we have discussed it as such. My view would be that in a sense the answer is yes. It is clearly arbitrary to have a requirement of 4 or 6 months for diagnosing ME but such a requirement is only relevant to research criteria. In the...