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  1. Samuel

    Covid-19 vaccines and vaccinations

    are there legal action political action social action on this.
  2. Samuel

    Covid-19 vaccines and vaccinations

    not sure if i am understanding right. please correct the following if you can if i got anything wrong. it seems to my seriously not working brain as if the state of play in many places, at least in usa, is that: - vaccines [original or omicron] help you get less sick from infection, reduce...
  3. Samuel

    Covid-19 vaccines and vaccinations

    why are they not for initial vaccinations? i get that original antigenic sin is not well understood, but wouldn't it be better to fixate on newer + older variants? i'd prefer that, but perhaps somebody with a working brain cell unlike mine now knows. this lay article seems a bit confused...
  4. Samuel

    UK: Energy-limiting conditions and Human Rights: The Chronic Illness Inclusion's submission to the UN as part of a 'shadow report'

    i will be interested in where this goes. i believe hr is a correct characterization and needed thing to do. both with respect to mass hr violation and mass hr atrocity crimes. and other stuff. one question from my experience is enforcement. do they take what they need to seriously vs. go...
  5. Samuel

    Long Covid in the media and social media 2022

    > Studying Long COVID Might Help Others With Post-Viral Fatigue Ailments i have come to nearly despise this type of sound bite. can't put finger on it, but i think it's the arrow of help. never mind the usual omissions about severity and progressiveness and persecution and sociopolitical...
  6. Samuel

    A neuro-metabolic account of why daylong cognitive work alters the control of economic decisions, 2022, Wiehler et al

    is the glutamate's observed behavior in the study essential in that brain location? what i mean is, can we reasonably surmise that it is an evolved response to protect something, or are we talking about something like normal operation creates glutamate in that location for whatever reason and...
  7. Samuel

    Prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in Australian primary care patients: only part of the story?, 2022, Orji et

    just wondering what the deal is with 100,000. [i am aware that fractions have been shown to improve reasoning that is related to the base rate fallacy or some such thing, but what i encountered of that result does not apply here.] i'd prefer a percentage, a proportion, or at least a...
  8. Samuel

    A neuro-metabolic account of why daylong cognitive work alters the control of economic decisions, 2022, Wiehler et al

    they call it a signalling molecule but does the glutamate serve a useful purpose or is it something like waste?
  9. Samuel

    Non-improvement in chronic fatigue syndrome: relation to activity patterns, uplifts and hassles, and autonomic dysfunction, 2022, Friedberg et al

    after all we have seen done to the curent attacked diseases and all that we know about history, i have come to believe that making the world better is not the result, in practice, of many of the psych* fields. experimental included. regardless of intent or beliefs, or incidental good done, it...
  10. Samuel

    Chronic Lyme Disease: a discussion of the epidemiological data

    unable to read entire thread but woul dlike to. has there been a consensus of any kind? can /untreated/ lyme result in severe progressive m.e.-like symptoms [or m.e.], highly multisystem, and other symptoms, for many years? [end on-topic part.] I grew up in in a top endemic Lyme disease...
  11. Samuel

    Intermittent fasting - restricting daily hours of eating - and ME/CFS

    can you please say what you mean by: > More restricted feeding time, usually 16/8 fasting, but occasionally 20/4 and rarely 36/12. i assume you mean soemthing like 16h no eating and 8h where you eat at whatever times during those 8h? [personal note: i often do something like [iiuc] 20/4...
  12. Samuel

    Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci, 2022,Hajdarevic et al

    ime this is key. i have a more nuanced and detailed response someplace but don't have it in me to search for it atm. sleep, including but not limited to circadian stuff, mediates pem. and pem can make sleep worse.
  13. Samuel

    Preprint: Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae, 2022, Swank et al

    this is probably a reply that has obvious answers from the paper or even op, but what is the half life of the protein in normals given the same methodology? also, do we have any surmises at whether the protein itself is harmful rather than downstream of something? also, does the result say...
  14. Samuel

    Adverse effects following...vaccination with mRNA...correlate with baseline enrichment of T and NK cell genes, 2022, Syenina et al

    i cannot read article. going by the quotes onlly here are they looking at fatigue in mice in addition to vaccine ae?
  15. Samuel

    Circadian rhythm disruption in [ME/CFS]: Implications for the post-acute sequelae of COVID-19, 2022, McCarthy

    fwiw tried using lights in late 1990s or so. designed for purpose in specific wavelength. did not change circadian.
  16. Samuel

    Children With PANS May Manifest POTS, 2022, Chan et al

    i think it is entirely natural that if you have pans, you might also have pots. and spatulas. lipkin and hornig and others did at least one paper on pandas [perhaps this: https://pubmed.ncbi.nlm.nih.gov/19668249/]. and i think hornig might have suggested at one point m.e. etiology could be...
  17. Samuel

    What differentiates ME/CFS from known primary mitochondrial diseases; could mitochondrial disease cause PEM?

    > muscle damage and progressive nature. It’s not the same condition clearly, but there can be some symptom overlap sometimes, although there are also some differences & specific symptoms doctors look for in mitochondrial disease such as the organ involvement. i'm confused here because muscle...
  18. Samuel

    What differentiates ME/CFS from known primary mitochondrial diseases; could mitochondrial disease cause PEM?

    if i hold my arm up briefly it becomes intolerable. whether supine or standing. idk if htat is consisten with m.e. or mito? i think same occurs using any muscle i try, such as bending foot toward shin while supine, legs and heels fully supported. [but to make it more complex i have...
  19. Samuel

    USA: National Institutes of Health (NIH) intramural ME/CFS study

    > Nath says he will not publish a preprint or release results in advance of publication i wonder why we can't get a small formal self-contained report that not impede the big paper. even a well-annotated subject flow diagram. least publishable unit is sardonic but perhaps it could be useful...
  20. Samuel

    BMJ: Impact of ME/CFS on the quality of life of people with ME/CFS and their partners and family members.... Vyas, Muirhead et al, 2022

    also those who do not have any survival capability due to lack of services. survival needs not met. i am facing this. that is, nobody able or willing to help if any and no government services that help. also children whose family, doctors, peers, teachers do not treat them as sick. [edit...
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