Search results

@RDP Let me echo @Trish's thanks to you for joining the forum and the discussion (it's great to have researchers here) and add my own thanks for the detailed responses to my many questions. I'd like to respond to a few of your points, grouped below into a few themes: Focusing on individual...

Thanks. Perhaps it would help if I summarise my questions here (modified after the helpful feedback, esp from @alex3619 and @Ravn). 1. Biology of causing ME/CFS 1.1 How do kynurenine, serotonin (and NAD?) leads to ME/CFS, particularly given the limited gene expression of IDO 2 (see below)...

Questions about the metabolic trap, and some concerns Thanks for the feedback. Is the genetic evidence robust? I'll start with my main concern about the trap, the strength of evidence for a genetic problem. Phair started this work with an intriguing approach of looking for genes where every...

I've come very late to the Metabolic Trap and have some questions about it, as well as one particular concern. But just to make sure I have got this right, could old hands at this game let me know if my summary, below is accurate? Thanks Summary: Robert Phair’s metabolic Trap idea aims to...

Thanks for all the replies. The main comment seems to me that, while the protocol clearly has an effect on (most0 patients, as well as biological effects, there are doubts as to whether this amounts to full post-exertions malaise. That view is reinforced by the two people to have undergone the...