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Even though the Perez article is a commentary (on Goldstein et al.) and not a peer-reviewed article, one would hope that Lancet editors would not want this "In my opinion" stuff in their journal(s).

LOL

Fauci remembers AIDS activist Larry Kramer for 'extraordinary courage' “He changed the relationship between the afflicted community and the scientific/regulatory community— we’ve got to be in [the same] tent.”

RIP ME/CFS could probably use a person like this. Larry Kramer, Playwright and Outspoken AIDS Activist, Dies at 84 https://www.nytimes.com/2020/05/27/us/larry-kramer-dead.html?action=click&module=Top%20Stories&pgtype=Homepage ‘We Loved Each Other’: Fauci Recalls Larry Kramer, Friend and...

Hopefully they’ll post it here. https://clinicaltrials.gov/ I want to know if this (kyn) is orally administered or via IV. If oral, maybe it won’t pass the blood brain barrier? If via IV, will it automatically pass the BBB? If it works, but folks will need daily IV infusions (or injections)...

Will this guy be able to get a job with this outstanding scholarship?

https://www.nytimes.com/2020/05/26/health/coronavirus-peter-piot.html?action=click&module=Spotlight&pgtype=Homepage A Virus-Hunter Falls Prey to a Virus He Underestimated Peter Piot, 71, one of the giants of Ebola and AIDS research, is still battling a coronavirus infection that hit him “like...

OK, about the alleles. 10 patients had HLA-DQB1*03:03 4 patients had HLA-C*07:04 12 patients had either DQB1 and/or C Which means that 2 patients were positive for both DQB1 and C. And therefore only 2 patients were positive HLA-C only (i.e. positive for HLA-C but negative for DQB1) Right...

They are talking about fatigue/exhaustion as symptoms, no? Not as a name for a disease. If they claim to have exhaustion and fatigue, I believe them.

I thought there were 4 candidates, glatiramer (Copaxone), SS31, suramin and SS19. I have not heard about any wide-spread allergic reactions to Copaxone other than from Rachel. But of the folks I have heard of who have tried glatiramer, it has been unsuccessful for treating MECFS. I'm...

Theoretical basis here The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS https://www.mdpi.com/2075-4418/9/3/82/htm

link here

Thanks. IDO2 mutation data from Ron Davis/Robert Phair group--"all 77 patients tested have a mutation in the IDO2 gene, this is "unusual"." I believe this a report of new data.

Hello, Bumping this thread with the hope that @Jonathan Edwards might be able to provide comment on this study...Thanks...

https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00612/full Inheritance of HLA-Cw7 Associated With Autism Spectrum Disorder (ASD) From Wikipedia--Cw7 serotype: C*07:01 to *07:06, *07:12, *07:14, *07:16 Something is going on here. I am not a geneticist--I guess that F & M used mol...

Summary article Do you want to treat arthritis? IDO2! Joanna Collison Nature Reviews Rheumatology volume 13, page197(2017) https://www.nature.com/articles/nrrheum.2017.33

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466478/ @Jonathan Edwards Given that people with MECFS apparently have mutations in IDO2--do you think using IDO2-specific mAb will work for MECFS as it apparently does for RA? Did this pan out for RA?

Failure!!! “Psycho-education” from Psychos. Very important contribution from the Highly Regarded Journal of Pilot and Feasibility Studies [Not!]

From Twitter thread...