Search results

That seems accurate. 7% reduction in absolute risk, but that's influenced by how rare or common the event of dying in that timeframe is in general. But if ~17% of people died in the control group and ~10% died with exercise, that's more than a third less that died over the 8 years. And the...

R^2 of .019

ME Research UK – May e-newsletter Articles Link

Perspective: host factors variants and the underlying causes of long COVID Tirasak Pasharawipas Long COVID, also known as post-COVID syndrome (PCS), is characterized by persistent and unexplained symptoms that can occur not only in individuals who experienced severe symptoms during the acute...

R stresses me out because I'm not very familiar with it, so when I'm not in a patient mood I just use Python. Computer's away for the night, but I'll do a linear model tomorrow.

Here's with merging on all rows from both studies using TargetFullName. Spearman r of .23

Yes the fact that this is not a thing has been irritating me all day as I crudely try to match up genes from one study with a single other study. It basically feels like it would be free data if such a database existed. There are many 'omics studies that would be great to cross-reference...

Since they did the validation portion, it seemed worth checking if there was overlap between the 57 proteins in that part with the thousands in the first part and in Germain. There were overlaps in 51 genes between all three cohorts. In 19 genes, the fold change was in the same direction. Only...

@ME/CFS Skeptic My plot looks the same by the way. Here are the three genes that were changed in the same direction in both studies and had a q value less than .05 in both: Edit: Added links to GeneCards.

Yeah, I think it's good enough for a rough idea.

I think TargetFullName might be best actually. Multiple aptamers can be associated with the same gene identifier, but I assume they each have a unique TargetFullName. If matching on UniProt, if either dataset has multiple aptamers per UniProt ID, you'll get arbitrary pairs of measurements...

Oh, another identifier, didn't notice that one. I do get 672 with that. I'm going to try merging where any of the columns match. Could you explain this a bit more:

I'm running into the issue when merging with an inner join of not having a consistent identifier. If I merge on 'UniProt', I get 682 rows. If I merge on 'EntrezGeneSymbol' I get 655. If I merge on 'EntrezGeneID', I get 631. Not sure how yours is different from all of these. It's different...

IgA autoimmunity and coagulation among post-acute sequelae of SARS-CoV-2 infection (PASC) patients with persistent respiratory symptoms: a case-control study Claudia Gomes, Jonathan H. Whiteson, Fabio Ponzo, Rany Condos, Mila B. Ortigoza, Marisol Zuniga, Ana Rodriguez, David C. Lee [Line...

I was looking at that, wondering if BMI was the reason for the increase (matched for sex), but they seem pretty closely matched for BMI as well: HC: 24.0±2.6 ME/CFS: 24.4±4.2 Maybe the larger variance in BMI in the ME/CFS group could affect things? Edit: Oh, not perfectly matched for sex like...

Now published. In terms of the abstract, other than minor spelling and formatting changes, the only change was removing the mention of IL-8. ---- Background Several studies reported long-term consequences of severe COVID-19. However, pathophysiological mechanisms of Post-Acute Sequelae...

Exploring Genetic Susceptibility to Internalizing Symptoms within the DSM: Network Analysis Selka Sadiković, Ljiljana Mihić, Radomir Belopavlović, Bojana M. Dinić, Nada Tokodi, Nataša Vučinić, Mechthild Prinz, Zoran Budimlija & Snežana Smederevac [Line breaks added] Abstract This study...

54 ME/CFS and 27 HC. 6494 proteins tested. 751 with significant q values. Down: intracellular proteins, including histones, metabolic enzymes | Up: immune system, metabolism | Up or down: vascular function Controlling for metabotype (what is metabotype?) and SF-36 physical function score...

That's interesting. Hydrocortisone cured her fear of gaining weight? I feel like anorexia is one of the best examples of a condition your doctor would send you to a therapist to fix, yet a cheap medication did the job.

Just added.