What do you think of intrathecal il ten gene therapy? It looks like there are gonna be clinical trials of this soon. There was a clinical trial...
On another note, anybody know why neuroinflammation conditions are not treated as inflammatory conditions? Eg the neuro degenerative ones...
Oh nevermind, mtx activates microglia and astrocytes. Intrathecal steroids are given for cancer too? But, steroids also activate glia...
Uh I had a realisation that there are immune suppressants given intrathecally, for leukemia! Intrathecal methexotrate. And... As with rituximab...
@Jonathan Edwards also, am I right on this a small trial with a negative outcome is treated as that it is true, but a small trial with a positive...
Hey PEJE. 'This latter model of increasing insular glutamate was recently reverse translated to show that findings of “small fiber neuropathy”...
I saw a study saying resting during acute phase of virus infection more likely leads to cfs. Does anybody know what I'm looking for? Looking for...
It is just that they have no concept of how to gather reliable evidence for what they already believe. What does this mean? Sorry im late 5 years...
Thank fucking god I have a referral to see this guy good thing I found this. I'm unable to watch videos so I have no idea what happened in the...
Did pots end up with CFS with that FAABs test showing it was absoluteluseless? Yes I found the thread about it, hard to find gee. That halcyon guy...
Correction, NO is both pro and anti inflammatory
Wait sorry this is an important q so I'll make it a single post, central sensitization is not the same as central pain is it?
On a personal note, I just wNt to add my own ane dote. I have fibro with PEM same as cfs, meaning I can get permanently worse. And. I have been...
Hip Would it even be possible to find evidence for this? Given that glial activation is non specific right? So you would have a hard time ever...
Professor I was wondering your opinion on neuroinflammation, and a quick search of the forums show you're a skeptic. I know you say glia activate...
Failed replication in a sample size of like 3? Was it? It was tiny and look at voners comment
I didn't quite think it that far, did Goebel paper provide a way to check levels of antibodies? Also see the MG study, same thing no objective...
https://classic.clinicaltrials.gov/ct2/show/NCT05643794?recrs=abdf&type=Intr&cond=Fibromyalgia&draw=3&rank=11 If this trial works, fibro will be...
https://classic.clinicaltrials.gov/ct2/show/NCT05643794?recrs=abdf&type=Intr&cond=Fibromyalgia&draw=3&rank=11 Someone is moving ahead with the...
Prednisone doesn't cross the bbb though, or at least not much, do cytokines cross into bbb?
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