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  1. M

    Dry eyes, laryngopharyngeal reflux, pepsin

    I have a very long history of LPR and live in New York. So I have seen three of the top experts on LPR - the ENT Jamie Koufman, the ENT Jonathan Aviv, and the gastroenterologist Philip Katz. They all attribute the rise in the incidence of esophageal cancer to LPR. The mainstay of their...
  2. M

    Chloroquine and Hydroxychloroquine as treatments for Covid-19

    Attached is a newly released randomized, blinded, placebo-controlled study of hydroxychloroquine in mildly sick, hospitalized Covid patients in China. Sample size is fairly small at 62. One inclusion criteria was that oxygen saturation at baseline had to be above 93%. According to a...
  3. M

    Chloroquine and Hydroxychloroquine as treatments for Covid-19

    The attached study was published a day or two ago by a group of French doctors on the use of hydroxychloroquine and azithromycin to treat hospitalized Covid-19 patients. The study has a number of problems, most of which the authors acknowledge: It was not placebo-controlled or double-blinded...
  4. M

    Vagus Nerve Stimulation

    David Kem at the University of Oklahoma appears to have plans to launch a well-controlled trial on the use of a TENS device in the treatment of POTS and to see if it affects production of alpha-adrenergic receptor autoantibodies. https://clinicaltrials.gov/ct2/show/NCT03930914 I know POTS is...
  5. M

    David Systrom, researcher, Brigham and Women's Hospital, USA

    I tried once to follow the recommendation in the pamphlet to exercise, getting on a recumbent bike in the gym of my apartment building about two weeks after my iCPET. I pedaled for 3 minutes against slight resistance, at which point I stopped to hopefully prevent PEM. That did not work: I felt...
  6. M

    David Systrom, researcher, Brigham and Women's Hospital, USA

    Below is the text from the pamphlet Systrom's team provided to me after my initial visit late last year. It outlines the testing and treatment protocol he follows for ME/CFS patients. ----------------------------------------------------------------------------------- AUTONOMIC DYSFUNCTION...
  7. M

    Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes (2019) Lakhani et al.

    I don't have access to the full article, so I don't know if this is a valid question or not. But isn't one issue that could bias the results the tendency of multiple family members to go to the same doctor? This may raise the concordance rate of particular diagnosis codes within families, not...
  8. M

    ME and Intercranial Hypertension (IIH) or Pseudotumor Cerebri

    I have pulsatille tinnitus of fairly recent onset (last 6 months). So I was prescribed an MRI of the brain with and without contrast to rule out intercranial hypertension, brain tumor, and/or venous or arterial malformations. MRI was negative, so the ENT specialist concluded my tinnitus is...
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