“Dietary sodium may stimulate vasopressin secretion through extracellular osmolality or even by a direct effect of extracellular sodium on...
Could it be helpful to take some salt first thing in the morning? https://www.sciencedirect.com/science/article/pii/S2211124721001807...
Glutamate also increases cerebral blood flow which might be a compensatory mechanism that when working can keep a pwME in the more mild categories.
Could this be a clue as to why benzodiazepines seem to increase capacity/functionality acutely? This is anecdotal of course but it seems to at...
Quick search of the literature found that this gene is HIF-1a and hypoxia activated in cancer cells
Unfortunately Mestinon never helped me all that much in the past. Maybe it’s worth another shot though
https://pubmed.ncbi.nlm.nih.gov/27973551/ Rapamycin dephosphorylates ATG13 on paper but didn’t help me
From one paper I read in a quick Google search mTorC1 is directly upstream of p-ATG13
Just wanted to add that I tried Rapamycin for a few months a couple years ago and even though it never helped I stuck with it because some of us...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714170/ ATG13 has non-autophagic capabilities and it appears to be anti-viral and relate to...
@SNT Gatchaman They say it’s unexpected but I have seen eNOS come up at least once in the ME literature. This is a novel mechanism though. I’m...
@mariovitali
@JES I had almost the exact same reaction to NatTokinase/Bromelain. A hopeful start but definitely worse after a few days. The flu like symptoms...
New to me was the findings of high phenylalanine and low BH4. Ron also said they have other indications of low dopamine. Going to add Vitamin...
Are you hinting at a compound you know of? I’d be quite interested in taking a look at such a thing.
This is extremely interesting to me as hot baths and heating pads, along with ice alternatively, seem to allow my body to accept some help energy...
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