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NPY popped up on my radar recently too, though not from this^ study. <consults notes> It seems I fell down a rabbit hole after reading Cort's recent piece about the NZ researchers looking at a PVN theory...

@mariovitali Hi Mario, Themos pointed me here after a twitter discussion of TSPO (also with @wigglethemouse) I find TSPO very interesting for its link to both mitochondrial enzymes and neuroinflammation. The connection to hemin is further intriguing for a number of reasons. I'll be brief here...

For trauma-induced epigenetic changes to pass to offspring, they'd have to be expressed in the germ line cells. (right?) I'm sold on this theory! My grampa was kicked in the testes at the Battle of the Bulge! </sarcasm>

Mine has never been normal since I got sick, but it is variable and mixed. These days, the most common response is what most people here are reporting - an exaggerated startle response. However, sometimes I'll have none at all (at least not outwardly) in response to a stimuli that should trigger...