Small-ish detail, but the question asked was "Did you experience any harm while doing the LP?", not "Did you experience any harm as a result of...
I looked this up, and for anyone interested this review: "Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future...
Lobbying Cochrane's funders, which are mostly governmental bodies and some charities, seems like possibly one of the best options. Cochrane...
The questionnaire in its current state seems flawed in a few ways, but it at least seems better than other questionnaires used in ME/CFS I've...
I get the impression that the distinction between "supportive CBT" and "pace-style CBT" may not be as clear as it seems. Both of them would still...
Yes, I read that and wasn't impressed with that. Diagnostic criteria referring to instruments doesn't mean they're "proven", nor does being...
I think it's good IQWiG acknowledged how small the effect sizes are in the press release. I think that's something obvious but it's also very...
Thank you for engaging on the forum and getting involved in this @sarahtyson. Apologies if I missed anything in this thread, since I haven't read...
They say a difference of 6 is considered a clinically relevant effect for the CIS-20, and they cite this paper for that statement. I don't see...
Can they at least give an explanation as to why it's okay to write a review with a clinically unimportant "non-zero" effect as the effect of...
Good to hear
I've seen it pointed out that it can make responses that sound very plausible and as if it knows what it is talking about, but are still wrong or...
It notes that "Regarding the hypothesis formulation, a two-sided test problem is traditionally assumed. Exceptions include non-inferiority...
That's understandable. Unfortunately I don't know German, so I would struggle to submit my own comment, but it would be good if anyone can...
As suggested by @MSEsperanza I will also post the comments that I put in the pdf too, so they're easier to view and refer to, which follow on from...
This is the draft of comments I've written up. It got a bit long, so I put some of the less important or more duplicated points in an attached...
This all looks correct, great work. It looks like they relied on the PEM survey referred to in the iqwig preliminary report to determine how many...
I don't think that's exactly what they're saying here, although it sort of is. That's how it's categorized in table 54. So if it's a randomized...
I've had a not super thorough look at the google translated document (so I may be mistaken about some aspects). There's probably a lot to say...
They didn't find a clinically relevant effect size for GET vs SMC for the primary outcomes so I assume they saw no point in including a...
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