Alpha7 nicotinic acetylcholine receptor agonist PHA 568487 dampens inflammation in PBMCs from patients with newly discovered coronary artery disease.
Filip Mjörnstedt; Rebecka Wilhelmsson; Marcus Ulleryd; Maria Hammarlund; Göran Bergström; Anders Gummesson; Maria E Johansson
BACKGROUND
The...
SARS-CoV-2 Spike Protein Downregulates Cell Surface α7nAChR through a Helical Motif in the Spike Neck
Tommy S. Tillman; Qiang Chen; Vasyl Bondarenko; Jonathan A. Coleman; Yan Xu; Pei Tang
A deficiency of the functional α7 nicotinic acetylcholine receptor (α7nAChR) impairs neuronal and immune...
The Role Of Α7 Nicotinic Acetylcholine Receptors In Post-Acute Sequelae Of Covid-19
Skok
Post-Acute Sequelae of COVID-19 or Long COVID becomes evident some weeks to months following acute COVID-19. Symptoms include cognitive impairment and varying degrees of memory loss with no definitive...
levamisole is an allosteric modulator of a7nAchR
https://journals.sagepub.com/doi/pdf/10.1177/1178646917691738
https://onlinelibrary.wiley.com/doi/abs/10.1111/jpi.12235
https://pdfs.semanticscholar.org/490f/ec1709c39d335f18226144c80b33a9384bfb.pdf...
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