pH sensing at the intersection of tissue homeostasis and inflammation
Stephanie Hajjar; Xu Zhou
pH is tightly maintained at cellular, tissue, and systemic levels, and altered pH – particularly in the acidic range – is associated with infection, injury, solid tumors, and physiological and...
The mechanism of Long Covid (Post-Acute Sequelae of COVID-19; PASC) is currently unknown, with no validated diagnostics or therapeutics. SARS-CoV-2 can cause disseminated infections that result in multi-system tissue damage, dysregulated inflammation, and cellular metabolic disruptions.
The...
Measuring extracellular human brain pH and amino acid metabolism with hyperpolarized [1-13C]pyruvate
Alixander S Khan; Mary A McLean; Joshua D Kaggie; Ines Horvat-Menih; Tomasz Matys; Rolf F Schulte; Matthew Locke; Ashley Grimmer; Pascal Wodtke; Elizabeth Latimer; Amy Frary; Martin J Graves...
Looking over my blood tests, I see that the two times (a few years ago) my anion gap was calculated it was just above the normal range (e.g 18 when the range is 8 to 16). My son's anion gap was similarly at the high end of normal.
A high anion gap suggests that the blood is too acid - i.e...
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