Adrenergic dysfunction in patients with myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia: A systematic review and meta-analysis
Jolien Hendrix; Lara Fanning; Arne Wyns; Ishtiaq Ahmed; Madhura Shekhar Patil; Emma Richter; Jente Van Campenhout; Kelly Ickmans; Rembert Mertens; Jo...
Abstract
SARS-CoV-2 mRNA vaccination can entail chronic fatigue/dysautonomia tentatively termed post-acute COVID-19 vaccination syndrome (PACVS). We explored receptor autoantibodies and interleukin-6 (IL-6) as somatic correlates of PACVS.
Blood markers determined before and six months after...
Abstract
Raynaud’s phenomenon (RP) is a common vasospastic disorder that causes severe pain and ulcers, but despite its high reported heritability, no causal genes have been robustly identified.
We conducted a genome-wide association study including 5,147 RP cases and 439,294 controls, based...
The β1-adrenergic receptor links sympathetic nerves to T cell exhaustion
Abstract
CD8+ T cells are essential components of the immune response against viral infections and tumours, and are capable of eliminating infected and cancerous cells. However, when the antigen cannot be cleared, T cells...
Media story
Full headline: Tonix Pharmaceuticals Completes Clinical Phase of PREVAIL Proof-of-Concept Study of TNX-102 SL for the Treatment of Fibromyalgia-Type Long COVID
https://finance.yahoo.com/news/tonix-pharmaceuticals-completes-clinical-phase-110000281.html
Immune adsorption for the treatment of fatigue-dominant long-/post-COVID syndrome—a case series of standardized individual experimental therapy
Research letter / case series of 10 patients.
Announced English version not published yet.
So in lieu of an abstract here's a google translate link...
Review:
A Unifying Hypothesis of the Pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Recognitions from the finding of autoantibodies against ß2-adrenergic receptors
KlausWirtha CarmenScheibenbogen...
From Twitter this morning
Perhaps part of the ME big picture ?
https://www.cell.com/neuron/fulltext/S0896-6273(19)30652-X?_returnURL=https://linkinghub.elsevier.com/retrieve/pii/S089662731930652X?showall=true
Apologies, phone being glitchy this morning so couldn't t copy and paste heading
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