Title: Multi-omic insights from a multi-ancestry genome-wide meta-analysis of ankylosing spondylitis reveal novel pathways of disease susceptibility
Authors:
Matthew Brown, Zhixiu Li, Xin Wu, Nicholas Harvey, Jose Garrido-Mesa, Xiaobing Wang, Zhihao Xu, Geng Wang, Helena Marzo-Ortega, Dennis...
Title: Antigen-driven T cell responses in rheumatic diseases: insights from T cell receptor repertoire studies
Journal: Nature Reviews Rheumatology
Authors: Jose Garrido-Mesa & Matthew A. Brown
Affiliation: Department of Medical and Molecular Genetics, Faculty of Life Sciences and Medicine...
Abstract
Increasing rates of autoimmune and inflammatory disease present a burgeoning threat to human health1. This is compounded by the limited efficacy of available treatments1 and high failure rates during drug development2, highlighting an urgent need to better understand disease...
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