antidepressant

  1. R

    Agomelatine but not melatonin improves fatigue perception: A longitudinal proof-of-concept study, Pardini et al, 2014

    Chronic Fatigue Syndrome (CFS) represents a disabling condition characterized by persistent mental and physical fatigue, bodily discomfort and cognitive difficulties. To date the neural bases of CFS are poorly understood; however, mono-aminergic abnormalities, sleep–wake cycle changes and...
  2. SNT Gatchaman

    Lipid storage myopathy associated with sertraline is an acquired mitochondrial disorder with respiratory chain deficiency, 2024, Hedberg-Oldfors+

    Lipid storage myopathy associated with sertraline treatment is an acquired mitochondrial disorder with respiratory chain deficiency Hedberg-Oldfors, Carola; Lindgren, Ulrika; Visuttijai, Kittichate; Shen, Yan; Ilinca, Andreea; Nordström, Sara; Lindberg, Christopher; Oldfors, Anders Lipid...
  3. rvallee

    Findings From a Survey of 530 British Antidepressant Users

    Antidepressant users report urgent need for services to assist with withdrawal. https://www.psychologytoday.com/gb/blog/psychiatry-through-the-looking-glass/202309/findings-from-a-survey-of-530-british In a survey of British antidepressant users, 70% experienced "severe withdrawal effects"...
  4. Shadrach Loom

    Review Cochrane review: antidepressants used to treat chronic pain

    https://www.cochrane.org/CD014682/SYMPT_how-effective-are-antidepressants-used-treat-chronic-pain-and-do-they-cause-unwanted-effects Key messages • We are only confident in the effectiveness of one antidepressant: duloxetine. We found that a standard dose (60 mg) was effective, and that there...
  5. cassava7

    The serotonin theory of depression: a systematic umbrella review of the evidence, Moncrieff et al, 2022

    Joanna Moncrieff, Ruth E. Cooper, Tom Stockmann, Simone Amendola, Michael P. Hengartner & Mark A. Horowitz The serotonin hypothesis of depression is still influential. We aimed to synthesise and evaluate evidence on whether depression is associated with lowered serotonin concentration or...
  6. Cheshire

    Do antidepressants work? Jacob Stegenga

    Some interresting considerations about trials methodology (CoI, selectivity in publishing trials with positive results, gap between patients selected and real life patients, scales, what is used as a placebo...) Rings a bell...
  7. Hutan

    Use of antidepressants for/with ME/CFS?

    The online guidance to doctors that I am reviewing has the following section about the use of antidepressants as treatments for ME/CFS: 1. The use of antidepressants in CFS has not shown a significant benefit:2 · There can be similarities in symptoms between CFS, depression, and...
  8. Andy

    Medscape: More Evidence Anticholinergic Meds Boost Dementia Risk

    https://www.medscape.com/viewarticle/896005
  9. Arnie Pye

    The drugs do work: antidepressants are effective, study shows

    Link to whole paper : http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(17)32802-7.pdf Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis Summary Background...
  10. Andy

    Article: "This is why a third of antidepressants are prescribed for something else"

    https://mosaicscience.com/story/off-label-antidepressants-prescribed-IBD-cancer-pain
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