antimicrobial peptides

Circulating Antimicrobial Peptides as Biomarkers of Inflammation and Airway Dysfunction After Marathon Running Marie-Therese Lingitz, Hannes Kühtreiber, Lisa Auer, Michael Mildner, Claus G. Krenn, Clemens Aigner, Bernhard Moser, Christine Bekos, Hendrik Jan Ankersmit [Line breaks added]...

Abstract For decades, antigen presentation on major histocompatibility complex class I for T cell-mediated immunity has been considered the primary function of proteasome-derived peptides1,2. However, whether the products of proteasomal degradation play additional parts in mounting immune...

Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system (CNS), the pathophysiology of which remains unclear and for which there is no definitive cure. Antimicrobial peptides (AMPs) are immunomodulatory molecules expressed in various tissues, including the CNS...

Proteomic analysis of post-COVID condition: Insights from plasma and pellet blood fractions Alejandro Seco-González, Paula Antelo-Riveiro, Susana B. Bravo, P.F. Garrido, M.J. Domínguez-Santalla, E. Rodríguez-Ruiz, Á. Piñeiro, R. Garcia-Fandino Background Persistent symptoms extending beyond...

Peptides from non-immune proteins target infections through antimicrobial and immunomodulatory properties Marcelo D.T. Torres; Angela Cesaro; Cesar de la Fuente-Nunez Encrypted peptides (EPs) have been recently described as a new class of antimicrobial molecules. They have been found in...

Infection and chronic disease activate a systemic brain-muscle signaling axis Editor’s summary Neuroinflammation can cause symptoms outside of the central nervous system (CNS), including muscle pain and fatigue, yet how inflammatory signals in the brain are communicated to muscle remains to be...

Now published: Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect function of stem cell derived cardiomyocytes, 2024, Sinclair+']link here[/URL] Preprint Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect the function of...

Lipidomics signature in post-COVID patient sera and its influence on the prolonged inflammatory response Abstract Background: The ongoing issues with post-COVID conditions (PCC), where symptoms persist long after the initial infection, highlight the need for research into blood lipid changes...

Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation Lee EY; Srinivasan Y; de Anda J; Nicastro LK; Tükel Ç; Wong GCL; Pathological self-assembly is a concept that is classically...

Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes Zhang, Yue; Bharathi, Vanthana; Dokoshi, Tatsuya; de Anda, Jaime; Ursery, Lauryn Tumey; Kulkarni, Nikhil N.; Nakamura, Yoshiyuki; Chen, Jonathan; Luo, Elizabeth W...

Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids Diamond G, Molchanova N, Herlan C, Fortkort JA, Lin JS, Figgins E, Bopp N, Ryan LK, Chung D, Adcock RS, Sherman M, Barron AE Viral infections, such as those caused by Herpes Simplex Virus-1 (HSV-1) and SARS-CoV-2...