Type I interferons and endoplasmic reticulum stress in health and disease
Sprooten; Garg
Type I interferons (IFNs) comprise of pro-inflammatory cytokines created, as well as sensed, by all nucleated cells with the main objective of blocking pathogens-driven infections. Owing to this broad range...
SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19
Guarnieri; Haltom; Albrecht; Lie; Olali; Widjaja; Ranshing; Angelin; Murdock; Wallace
To determine the effects of SARS-CoV-2 infection on cellular metabolism, we conducted an exhaustive survey of the cellular metabolic...
Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture
Jonathan P. Davies; Athira Sivadas; Katherine R. Keller; Brynn K. Roman; Richard J.H. Wojcikiewicz; Lars Plate
Coronaviruses (CoV), including SARS-CoV-2, modulate host proteostasis...
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