butyrophylin

  1. Andy

    Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune... 2026 Karumanchi et al

    Full title: Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss Abstract B7 costimulatory family member Butyrophilin 2A2 (BTN2A2) is predominantly expressed by antigen presenting cells and...
  2. SNT Gatchaman

    Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children MIS-C, 2024, Bellos et al.

    Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children MIS-C Bellos, Evangelos and 97 others Multisystem inflammatory syndrome in children (MIS-C) is a rare condition following SARS-CoV-2 infection associated with intestinal manifestations. Genetic...
    • SNT Gatchaman
    • Thread
    • butyrophylin gamma-delta t cells gastrointestinal genetic polymorphisms gut barrier gut permeability mis-c
    • Replies: 1
    • Forum: Long Covid research
  3. Andy

    Butyrophilin-like 3 Directly Binds a Human Vγ4+ T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen 2019 Wilcox et al

    Highlights BTNL3 binds directly and specifically to Vγ4+ TCRs via its IgV domain The superantigen-like binding mode focuses on germline-encoded TCR regions In contrast, γδ TCR binding to a clonally restricted antigen is CDR3-mediated Mutagenesis indicates parallels with BTN3A1-mediated...
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