daratumumab

  1. Kalliope

    Open Norway: Plasma cell aimed treatment with daratumumab in ME/CFS - Haukeland University Hospital

    The ME/CFS research team at Haukeland University Hospital in Bergen, Norway (Fluge, Mella, Rekeland, Sørland etc) is recruiting 66 participants for a new placebo-controlled trial on Daratumumab as a potential treatment for ME/CFS. The duration for participants is 72 weeks. The participants will...
  2. John Mac

    Open Norway: Study of Daratumumab Injections for Patients with Moderate to Severe Chronic Fatigue Syndrome, 2025

    What is this study about? This clinical trial is focused on studying the effects of a medication called daratumumab on patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). ME/CFS is a condition characterized by extreme fatigue that doesn’t improve with rest and can worsen...
  3. J

    Daratumumab, isatuximab (CD38 drugs)

    Commercialisation of HLX15 (daratumumab) https://www.businesswire.com/news/home/20250206161649/en/Dr.-Reddy’s-enters-into-collaboration-with-Henlius-for-commercialization-of-HLX15-daratumumab-a-biosimilar-candidate-to-Darzalex®-Darzalex-Faspro®-in-the-U.S.-and-Europe
  4. SNT Gatchaman

    Relapsing-Remitting Immunotherapy Responsive Small-Fiber Neuropathy, 2024, Oaklander et al.

    Relapsing-Remitting Immunotherapy Responsive Small-Fiber Neuropathy Anne Louise Oaklander, Julia Allen, Nadja Dietliker, Einar P. Wilder-Smith OBJECTIVES To expand understanding of the pathogenesis, presentations, and treatment of initially idiopathic small fiber polyneuropathy (SFN). METHODS...
  5. J

    Efficacy of daratumumab in refractory primary Sjögren disease Nocturne 2023

    https://rmdopen.bmj.com/content/9/3/e003464 Here, we report the first two cases of patients with severe complications of SjD, refractory to RTX and successfully treated with daratumumab.
  6. ME/CFS Skeptic

    The most promising drugs for ME/CFS?

    With EMEC we are trying to set up a meeting with representatives of The European Federation of Pharmaceutical Industries and Associations (EFPIA). We are compiling a list of drugs that seem most promising for the treatment of ME/CFS and the pharmaceutical companies that make them. An example...
  7. Kalliope

    Open 2022 Pilot study in Norway - Daratumumab in ME/CFS

    Fluge et al are recruiting six moderate to severe ME patients for a pilot trial on Daratumumab. Participants need to be able to travel to Haukeland University Hospital in Bergen and been diagnosed according to the Canadian criteria from 2003. They need to be between 18 and 65 years old and...
  8. S

    Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus, 2020, Ostendorf et al.

    Summary Daratumumab, a human monoclonal antibody that targets CD38, depletes plasma cells and is approved for the treatment of multiple myeloma. Long-lived plasma cells are implicated in the pathogenesis of systemic lupus erythematosus because they secrete autoantibodies, but they are...
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