diffusion tensor imaging

Reduced microstructural white matter integrity is associated with the severity of physical symptoms in functional neurological disorder Gninenko; Müller; Aybek BACKGROUND Functional neurological disorder (FND) is linked to functional changes in brain networks without an underlying brain lesion...

https://www.medrxiv.org/content/10.1101/2025.04.08.25325108 Abstract Post-COVID Syndrome (PCS), also known as Long COVID, is characterized by persistent and often debilitating neurological sequelae, including fatigue, cognitive dysfunction, motor deficits, and autonomic dysregulation (Dani et...

Asymmetrical glymphatic dysfunction in patients with long Covid associated neurocognitive impairment- correlation with BBB disruption Chaganti, Joga R.; Talekar, Tanush K.; Brew, Bruce James BACKGROUND AND PURPOSE The glymphatic system, a waste clearance pathway, has been implicated in several...

Structural brain changes in post-COVID condition and its relationship with cognitive impairment Pacheco-Jaime, Laura et 52 al. It has been estimated that ~4% of individuals infected with SARS-CoV-2 will be diagnosed with post-COVID condition. Previous studies have evidenced the presence of...

Large-scale brain network analysis reveals functional-structural dissynchrony in HIV-associated asymptomatic neurocognitive disorders: Functional disturbances precede structural changes Zhongkai Zhou; Wenru Gong; Hong Hu; Fuchun Wang; Hui Li; Fan Xu; Hongjun Li; Wei Wang BACKGROUND In the era...

Hypothalamus Connectivity in Adolescent Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Hollie Byrne; Sarah J. Knight; Elisha K. Josev; Adam Scheinberg; Richard Beare; Joseph Y. M. Yang; Stuart Oldham; Katherine Rowe; Marc L. Seal Adolescent Myalgic Encephalomyelitis/Chronic Fatigue Syndrome...

Differences in brain structure and cognitive performance between patients with long-COVID and those with normal recovery Nelson; Farah; Grier; Su; Chen; Sossi; Sekhon; Stoessl; Wellington; Honer; Lang; Silverberg; Panenka BACKGROUND The pathophysiology of protracted symptoms after COVID-19 is...

Impaired glymphatic function as a biomarker for subjective cognitive decline: An exploratory dual cohort study Yuxia Li, Luyao Wang, Jiayi Zhong, Huanyu Xu, Ying Han, Chuantao Zuo, Jiehui Jiang Background: Subjective cognitive decline (SCD) has been recognized as a potential risk stage for...

Introduction: There is a growing interest in the effect of Long-COVID (LC) on cognition, and neuroimaging allows us to gain insight into the structural and functional changes underlying cognitive impairment in LC. We used multimodal neuroimaging data in combination with neuropsychological...

Diffusion tensor analysis of white matter tracts is prognostic of persisting post-concussion symptoms in collegiate athletes Bertò; Rooks; Broglio; McAllister; McCrea; Pasquina; Giza; Brooks; Mihalik; Guskiewicz; Goldman; Duma; Rowson; Port; Pestilli BACKGROUND AND OBJECTIVES After a concussion...

Loss of white matter integrity mediates the association between cortical cerebral microinfarcts and cognitive dysfunction: A longitudinal study Jiannan Huang; Megan Oh; Caroline Robert; Xiangyuan Huang; Marco Egle; Daniel J Tozer; Christopher Chen; Saima Hilal Cortical cerebral microinfarcts...

Blood brain barrier disruption and glutamatergic excitotoxicity in post-acute sequelae of SARS COV-2 infection cognitive impairment: potential biomarkers and a window into pathogenesis Chaganti, Joga; Poudel, Govinda; Cysique, Lucette Adeline; Dore, Gregory J.; Kelleher, Anthony; Matthews, Gael...

Neuroinflammatory imaging markers in white matter: insights into the cerebral consequences of post-acute sequelae of COVID-19 PASC Sean Clouston; Chuan Huang; Jia Ying; Zennur Sekendiz; Minos Kritikos; Ashley Fontana; Lev Bangiyev; Benjamin Luft Symptoms of coronavirus disease 2019 (COVID-19)...

Effects of Low-Level Blast on Neurovascular Health and Cerebral Blood Flow: Current Findings and Future Opportunities in Neuroimaging Kilgore, Madison O.; Hubbard, W. Brad Low-level blast (LLB) exposure can lead to alterations in neurological health, cerebral vasculature, and cerebral blood...

Glymphatic system dysfunction in recovered patients with mild COVID-19: A DTI-ALPS study Lin Wu; Zhi Zhang; Xiao Liang; Yao Wang; Yuan Cao; Meng Li; Fuqing Zhou Central nervous sequelae are often reported in recovered patients with COVID-19. It is not clear whether recovered COVID-19 patients...

MRI with generalized diffusion encoding reveals damaged white matter in patients previously hospitalized for COVID-19 and with persisting symptoms at follow-up Boito, Deneb; Eklund, Anders; Tisell, Anders; Levi, Richard; Özarslan, Evren; Blystad, Ida There is mounting evidence of the long-term...

No evidence for the association between COVID-19 and neuroinflammation: A diffusion basis spectrum imaging study. Wei Zhang; Aaron J Gorelik; Qing Wang; Sara A Norton; Tamara Hershey; Janine D Bijsterbosch; Ryan Bogdan COVID continues to be a major international public health concern, the...

What lies beneath: White matter microstructure in pediatric myalgic encephalomyelitis/chronic fatigue syndrome using diffusion MRI Elisha K. Josev; Jian Chen; Marc Seal; Adam Scheinberg; Rebecca C. Cole; Katherine Rowe; Lionel Lubitz; Sarah J. Knight Recent studies in adults with myalgic...

Free-water-corrected diffusion and adrenergic/muscarinic antibodies in myalgic encephalomyelitis/chronic fatigue syndrome Yukio Kimura; Wakiro Sato; Norihide Maikusa; Miho Ota; Yoko Shigemoto; Emiko Chiba; Elly Arizono; Hiroyuki Maki; Isu Shin; Keiko Amano; Hiroshi Matsuda; Takashi Yamamura...

Abnormal brain diffusivity in participants with persistent neuropsychiatric symptoms after COVID-19 Huajun Liang; Thomas Ernst; Kenichi Oishi; Meghann C. Ryan; Edward Herskovits; Eric Cunningham; Eleanor Wilson; Shyamasundaran Kottilil; Linda Chang Objectives We aimed to compare brain white...