Reversible reduction in brain myelin content upon marathon running
Ramos-Cabrer, Pedro; Cabrera-Zubizarreta, Alberto; Padro, Daniel; Matute-González, Mario; Rodríguez-Antigüedad, Alfredo; Matute, Carlos
Here we use magnetic resonance imaging to study the impact of marathon running on brain...
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5131664
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disorder with no known underlying mechanisms, diagnostic tools, or treatments.
Multiple areas of dysfunction have been extensively studied, but rarely...
FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss
Bryn M. Owen, Xunshan Ding, Donald A. Morgan, Katie Colbert Coate, Angie L. Bookout, Kamal Rahmouni, Steven A. Kliewer, David J. Mangelsdorf
The mechanism by which pharmacologic administration of the...
The Nuanced Metabolic Functions of Endogenous FGF21 Depend on the Nature of the Stimulus, Tissue Source, and Experimental Model
Redin A. Spann, Christopher D. Morrison and Laura J. den Hartigh
Fibroblast growth factor 21 (FGF21) is a hormone that is involved in the regulation of lipid, glucose...
Understanding the Physiology of FGF21
Ffolliott Martin Fisher and Eleftheria Maratos-Flier
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based...
Abstract
Although most patients recover from acute COVID-19, some experience postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of PASC is a syndrome called “long COVID-19,” reminiscent of myalgic encephalomyelitis/chronic fatigue syndrome...
An ad is currently being circulated in Swedish ME groups on social media, a research study led by prof Jonas Bergquist at Uppsala University that is currently recruiting.
It's a study on altered energy metabolism in ME/CFS, focusing mainly on lactate, glucose and hypoxanthine.
(I couldn't find...
Research in algae, but interesting .
Given phosphate' s role in energy metabolism perhaps worth exploring in other organisms
https://phys.org/news/2020-10-phosphate-polymer-cornerstone-metabolic.amp
Mod note: Moved from this thread
My experience is both during and after. I would describe 3 phases:
1. During exertion - rapid muscle fatiguability (and increasing pain) that means I can't go on using a muscle for long before it loses strength. So right from the beginning of my illness...
I wasn’t sure where to put this. It is general background information about metabolism, but since it is directly relevant to energy production in PWME and hence fatigue, I put it here.
Recently I needed to refresh my memory about how some amino acids are broken down for energy.
I thought I...
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