evolution

Sequence modeling and design from molecular to genome scale with Evo Eric Nguyen; Michael Poli; Matthew G. Durrant; Brian Kang; Dhruva Katrekar; David B. Li; Liam J. Bartie; Armin W. Thomas; Samuel H. King; Garyk Brixi; Jeremy Sullivan; Madelena Y. Ng; Ashley Lewis; Aaron Lou; Stefano Ermon...

A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes Sanderson, Theo; Hisner, Ryan; Donovan-Banfield, I’ah; Hartman, Hassan; Løchen, Alessandra; Peacock, Thomas P.; Ruis, Christopher Molnupiravir, an antiviral medication that has been widely used against SARS-CoV-2, acts...

Moger-Reischer, R.Z., Glass, J.I., Wise, K.S. et al. Evolution of a minimal cell. Nature (2023). https://doi.org/10.1038/s41586-023-06288-x Received 15 September 2021 Accepted 06 June 2023 Published 05 July 2023 Possessing only essential genes, a minimal cell can reveal mechanisms and...

Thermosensitivity of translation underlies the mammalian nocturnal-diurnal switch Andrew David Beale; Nina M Rzechorzek; Andrei Mihut; Aiwei Zeng; Nicola J Smyllie; Violetta Pilorz; Rose Richardson; Mads F Bertlesen; Nathan R James; Shaline V Fazal; Zanna Voysey; Jerry Pelletier; Priya Crosby...

In European and many African, Middle Eastern and southern Asian populations, lactase persistence (LP) is the most strongly selected monogenic trait to have evolved over the past 10,000 years1. Although the selection of LP and the consumption of prehistoric milk must be linked, considerable...