-
New Forum Software Installed (Still a few issues but reopening the forum) More details.
fbxl4
-
A mitochondrial SCF‐FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease, 2023, Cao+
A mitochondrial SCF‐FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease Mitophagy is a fundamental quality control mechanism of mitochondria. Its regulatory mechanisms and pathological implications remain poorly understood. Here, via...- SNT Gatchaman
- Thread
- bnip3 fbxl4 mitochondria mitophagy ubiquitin
- Replies: 0
- Forum: Other health news and research
-
Genetics: FBXL4
DecodeME candidate ME/CFS gene ******************** FBXL4 (Tier 2) • Protein: F-box/LRR-repeat protein 4. UniProt. GeneCards. • Molecular function: Component of the mitochondria-localised SCF-FBXL4 ubiquitin E3 ligase complex. This complex restricts mitophagy by controlling the degradation...- Hutan
- Thread
- decodeme fbxl4 genetics mitochondria
- Replies: 11
- Forum: Possible causes and predisposing factor discussion