Background: Several studies suggested an important role of the gut microbiota in the pathophysiology of neurological disorders, implying that alteration of the gut microbiota might serve as a treatment strategy. Fecal microbiota transplantation (FMT) is currently the most effective gut...
Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain
Hao-Ming Xu,1 Hong-Li Huang,1 You-Lian Zhou,1 Hai-Lan Zhao,1 Jing Xu,1 Di-Wen Shou,1 Yan-Di Liu,1 Yong-Jian Zhou,1 and Yu-Qiang Nie
https://www.hindawi.com/journals/grp/2021/6699268/
The intestinal virome and viral immune responses in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) patients after faecal microbiota transplantation (FMT) (POWELLU19ME)
University of East Anglia
Norwich Medical School...
Research news from Canada:
"In a phase I clinical trial, the research team is the first in Canada to study the use of fecal transplants to alter a cancer patient’s microbiome and improve their response to anti-PD1 immunotherapy drugs."...
https://www.sciencedirect.com/science/article/pii/S2452231719300077?via=ihub&fbclid=IwAR3xQzNGvlwamXbx_F9ZKohGcOiIMGOIbXnz4WgVwZqScW3c-CoS9zTRx64
Note that this is a study written by the owners of the clinic where the FMT is done. I'd take with a pinch of salt.
This may at least partly explain the patchy results in FMT trials: not all poo is created equal.
Science Alert article: There Are People Amongst Us Whose 'Super Poop' Can Treat Serious Diseases...
Since fecal transplants came up at IiME13 this week, this seemed topical.
The article, https://mobile.nytimes.com/2018/06/02/health/fecal-transplants-bacteria-antibiotics.html
The paper, https://www.nejm.org/doi/full/10.1056/NEJMc1803103
Paywalled at https://jamanetwork.com/journals/jama/article-abstract/2664458
Discussed here - https://www.medscape.com/viewarticle/889258?src=soc_fb_171202_mscpedt_news_mdscp_mdscp_coloncancer (You may need a Medscape account to access it)
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