histamine

Highlights Mononuclear cells are primary drivers of the exercise response in skeletal muscle • Release of histamine from skeletal muscle during exercise from mast cells • Histamine receptor antagonists impair post-exercise muscle glycogen resynthesis • Exercise-induced transcriptional...

Antihistamines improve cardiovascular manifestations and other symptoms of long-COVID attributed to mast cell activation Fabrizio Salvucci, Roberto Codella, Adriana Coppola, Irene Zacchei, Gabriella Grassi, Maria Luisa Anti, Nicolita Nitisoara, Livio Luzi, Carmine Gazzaruso Introduction...

Abstract Histamine intolerance, also referred to as enteral histaminosis or sensitivity to dietary histamine, is a disorder associated with an impaired ability to metabolize ingested histamine that was described at the beginning of the 21st century. Although interest in histamine intolerance has...

The Intriguing Role of Histamine in Exercise Responses 2017 Luttrell and Halliwill Brief Abstract In humans, histamine is a molecular transducer of physical activity responses, and antihistamines modify more than 25% of the genes responding to exercise. Although the upstream signal that results...

A role for bacterial histamine in abdominal pain Gut bacteria have been implicated in the genesis of chronic pain disorders; however, the underlying mechanisms remain unclear. In new work, De Palma and colleagues show that histamine, a known neuroimmune modulator, is produced by gut bacteria and...

Paywall, https://link.springer.com/article/10.1007/s00421-021-04645-0

"We have presented evidence that patients with ISM exhibit a significant and intercorrelated rise in histamine and tryptase following exercise consistent with the conclusion that physical activity can induce mast cell mediator release. Furthermore, the increase in these mediators in...