Preprint posted on MedRxiv, now posted with new title on SSRN, see post #4
Integrative Genome-Wide Association Studies of COVID-19 Susceptibility and Hospitalization Reveal Risk Loci for Long COVID
Zhongshan Cheng
Abstract
Long COVID presents a significant public health challenge...
HLA-DQB1*05:03 is associated with an increased risk of COVID-19 progression in the Bulgarian population
Lukanov; Mihaylova; Al Hadra; Lesichkova; Georgieva; Popov; Krasteva; Mondeshki; Naumova
The SARS‐CoV‐2 outbreak represents a global health problem. The different infection rates are heavily...
Immune exhaustion in ME/CFS and long COVID
Natalie Eaton-Fitch; Penny Rudd; Teagan Er; Livia Hool; Lara Herrero; Sonya Marshall-Gradisnik
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are debilitating multisystemic conditions sharing similarities in immune...
Abstract
The pathogenesis of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) remains unclear, though increasing evidence suggests inflammatory processes play key roles. In this study, single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) was used to...
https://www.researchsquare.com/article/rs-3335919/v1
Article
Immune cell proteomes of Long COVID patients have functional changes similar to those in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Katie Peppercorn1
Christina D. Edgar1
Torsten Kleffmann1
Warren. P Tate1
Email
1...
Objective
Functional somatic syndromes (FSS) are highly prevalent across all levels of healthcare. The fact that they are characterised by medically unexplained symptoms, such as fatigue and pain, raises the important question of their underlying pathophysiology. Psychosocial stress represents...
Full title: Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci
Abstract
The etiology of myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is unknown, but...
published in frontiers in Medicine - Family Medicine and Primary Care
Results: The overall response rate by Fatigue score was 55.0% (22 of 40 patients). Fatigue score and other outcome variables showed significant improvements compared to baseline. The SF-36 Physical Function score increased...
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