huntingtons

  1. Wyva

    Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease, 2024, Helabad et al

    Mahdi Bagherpoor Helabad, Irina Matlahov, Raj Kumar, Jan O. Daldrop, Greeshma Jain, Markus Weingarth, Patrick C. A. van der Wel & Markus S. Miettinen Abstract Neurodegeneration in Huntington’s disease (HD) is accompanied by the aggregation of fragments of the mutant huntingtin protein, a...
  2. Sly Saint

    Beta-blocker drugs may slow Huntington's disease progression

    Beta-blocker drugs may slow Huntington's disease progression
  3. Andy

    Targeting Mitochondrial Network Disorganization is Protective in C. elegans Models of Huntington’s Disease, 2021, Machiela et al

    In worms. Abstract Huntington’s disease (HD) is an adult-onset neurodegenerative disease caused by a trinucleotide CAG repeat expansion in the HTT gene. While the pathogenesis of HD is incompletely understood, mitochondrial dysfunction is thought to be a key contributor. In this work, we...
  4. R

    Huntington’s breakthrough may stop disease

    I thought some here might find this article interesting. I posted a few interesting excerpts from the article. http://www.bbc.com/news/health-42308341 An experimental drug, injected into spinal fluid, safely lowered levels of toxic proteins in the brain. The research team, at University...
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