ighv

  1. Chandelier

    Preprint Persistent Immune Dysregulation during Post-Acute Sequelae of COVID-19 … Antibodies Targeting Envelope and Nucleocapsid Proteins, 2025, Kwisa et al.

    Persistent Immune Dysregulation during Post-Acute Sequelae of COVID-19 is Manifested in Antibodies Targeting Envelope and Nucleocapsid Proteins https://www.biorxiv.org/content/10.1101/2025.08.18.670908v1 Abstract Post-Acute Sequelae of SARS-CoV-2 infection (PASC) syndrome or “Long COVID”...
  2. Mij

    Preprint Defective peripheral B cell tolerance leads to dysregulated B cell responses in Fibromyalgia Syndrome, 2025, Rachael Bashford-Rogers et al

    Abstract Fibromyalgia syndrome (FMS) is a chronic pain disorder characterised by widespread musculoskeletal pain, fatigue, and cognitive dysfunction, with no definitive biomarkers or mechanism-based treatments. Emerging evidence suggests that immune dysregulation may contribute to the FMS...
  3. SNT Gatchaman

    Proteomics Reveals That Vitamin D Deficiency Leads to Immunoglobulin Abnormalities and Immune Dysregulation in Patients with [LC], 2025, Ji+

    Proteomics Reveals That Vitamin D Deficiency Leads to Immunoglobulin Abnormalities and Immune Dysregulation in Patients with Post-COVID-19 Condition Wenrui Ji; Xiaomin Xie; Guirong Bai; Yalei Fan; Yanting He; Li Zhang; Haiyan Zhou; Ling Li; Huan Li Vitamin D (VD) levels are closely related to...
  4. Nightsong

    Deep Sequencing of BCR Heavy Chain Repertoires in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Ryback et al

    Now published: see here Abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a common and debilitating chronic illness of unknown aetiology. Chronic infection and autoimmune responses have been proposed as two mechanisms that potentially underlie the pathogenesis of ME/CFS...
  5. SNT Gatchaman

    A blood-based mRNA signature distinguishes people with Long COVID from recovered individuals, 2024, Missailidis, Annesley+

    A blood-based mRNA signature distinguishes people with Long COVID from recovered individuals Missailidis, Daniel; Ebrahimie, Esmaeil; Mohammadi-Dehcheshmeh, Manijeh; Allan, Claire; Sanislav, Oana; Fisher, Paul Robert; Gras, Stephanie; Annesley, Sarah Jane Long COVID is a debilitating condition...
    • SNT Gatchaman
    • Thread
    • annesley icos ighv la trobe university lilrb missailidis s1pr sphingolipids transcriptomics
    • Replies: 13
    • Forum: Long Covid research
  6. SNT Gatchaman

    Post-COVID exercise intolerance ...associated ... capillary alterations and immune dysregulations in skeletal muscles, 2023, Aschman, Scheibenbogen +

    Now published - see post Preprint Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles Tom Aschman, Emanuel Wyler, Oliver Baum, Andreas Hentschel, Franziska Legler, Corinna Preusse, Lil Meyer-Arndt...
    • SNT Gatchaman
    • Thread
    • capillaries capillary basement thickness cd169 ighv immune dysfunction laminins long covid macrophages microcirculation muscle muscle biopsy muscle weakness t-cells
    • Replies: 12
    • Forum: Long Covid research
  7. LarsSG

    Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC)..., 2022, Kell & Pretorius et al

    Abstract Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID, has become a major global health and economic burden. Previously, we provided evidence that there is a significant insoluble fibrin amyloid microclot load in the circulation of individuals with long COVID...
    • LarsSG
    • Thread
    • fibrin ighv immunoglobulin kallikreins kell long covid microclots pf4 platelets pretorius
    • Replies: 1
    • Forum: Long Covid research
  8. Andy

    Skewing of the B cell receptor repertoire in myalgic encephalomyelitis/chronic fatigue syndrome, 2021, Sato et al

    Highlights • ME/CFS is characterized by skewed B cell receptor gene usage. • Upregulation of specific IGHV genes correlated to infection-related episodes at onset. • Plasmablasts of ME/CFS patients upregulated interferon response genes. • B cell receptor repertoire analysis can provide a useful...
    • Andy
    • Thread
    • 2021 autoimmunity b cell receptor b cells biomarker corticosteroids genetics hydrocortisone ighv japan me/cfs paper sato takashi yamamura wakiro sato
    • Replies: 26
    • Forum: ME/CFS research
  9. Andy

    Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS, 2020, Lipkin et al

    Open access, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236148
    • Andy
    • Thread
    • 2020 b cell receptor b cells camp ighv kinase inhibitor lipkin lymphoma me/cfs paper proteomics
    • Replies: 31
    • Forum: ME/CFS research
  10. Sly Saint

    Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns, 2018, Trivedi, Klimas et al

    Public on Jul 23, 2018 https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE111183 eta: It's an article in PLOSone Published: July 23, 2018 https://doi.org/10.1371/journal.pone.0201066 full study here: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201066
    • Sly Saint
    • Thread
    • 2018 epigenetics genomics ighv immunology klimas me/cfs methylation paper
    • Replies: 2
    • Forum: ME/CFS research
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