il-1b

  1. SNT Gatchaman

    Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications, 2025, Semo+

    Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications Semo, Dilvin; Shomanova, Zornitsa; Sindermann, Jürgen; Mohr, Michael; Evers, Georg; Motloch, Lukas J.; Reinecke, Holger; Godfrey, Rinesh; Pistulli, Rudin Cardiovascular...
    • SNT Gatchaman
    • Thread
    • caspase caspase-1 glutathione grp78 il-1b immunoparalysis inflammasome mitochochria monocytes mtdna oxidative stress reactive oxygen species seahorse tlr-4 tlr-9
    • Replies: 2
    • Forum: Long Covid research
  2. SNT Gatchaman

    Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis, 2022, Eltobgy, Amer et al.

    Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis Eltobgy, Mostafa M.; Zani, Ashley; Kenney, Adam D.; Estfanous, Shady; Kim, Eunsoo; Badr, Asmaa; Carafice, Cierra; Daily, Kylene; Whitham, Owen; Pietrzak, Maciej; Webb, Amy; Kawahara...
  3. forestglip

    Thesis Towards precision medicine for (long) COVID, 2025, Baalbaki

    Towards precision medicine for (long) COVID Perspectives on pharmacotherapy and molecular mechanisms N. Baalbaki [Line breaks added] Abstract This thesis shed light on the complex and heterogeneous nature of (long) COVID. It contributed to the characterization of both acute COVID-19 and long...
    • forestglip
    • Thread
    • barrier function epithelial ifny il-1b long covid nasal epithelium pulmonary function smurf1 wound healing
    • Replies: 1
    • Forum: Long Covid research
  4. forestglip

    Thesis Clinical, histopathological, and radiological characterization of post-acute sequelae of COVID-19, 2025, Czech

    Clinical, histopathological, and radiological characterization of post-acute sequelae of COVID-19 Anna Czech Abstract Numerous patients exhibit enduring symptoms following a Coronavirus Disease 2019 (COVID-19) infection, termed Post-Acute Sequelae of COVID-19 (PASC). The typical manifestations...
    • forestglip
    • Thread
    • cd4+ fev1 fibrinous alveolitis forced vital capacity il-1b lav long covid macrophages organizing pneumonia oxygen pulse t cells viral persistence
    • Replies: 0
    • Forum: Long Covid research
  5. forestglip

    Exploring the shared mechanism of fatigue between [lupus] and [ME/CFS]: monocytic dysregulation..., 2024, Zheng et al

    Exploring the shared mechanism of fatigue between systemic lupus erythematosus and myalgic encephalomyelitis/chronic fatigue syndrome: monocytic dysregulation and drug repurposing Daisi Zheng, Xiaolong Li, Qingmiao Zhu, Zhiyan Huang, Peicheng Wang, Ting Zhao [Provisionally accepted] Edit: Now...
    • forestglip
    • Thread
    • acmc-20mvek camptothecin ccl2 ifih1 il-1b lupus me/cfs n-acetyl-l-cysteine nac simvastatin stat1 suloctidil systemic lupus erythematosus tlr-2
    • Replies: 5
    • Forum: ME/CFS research
  6. forestglip

    Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients, 2024, Tilikete et al

    Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients Chafik Tilikete, Imen Zamali, Zeineb Meddeb, Ghassen Kharroubi, Soumaya Marzouki, Tarak Dhaouadi, Ahlem Ben Hmid, Samar Samoud, Yousr Galai, Selma Charfeddine, Leila Abid, Salem Abdessalem, Jihène...
    • forestglip
    • Thread
    • acute infection cytokines dyspnea endothelial dysfunction fatigue ifny il-10 il-12p70 il-1a il-1b il-27 il-6 il-8 inflammation ip-10 long covid mcp-1 memory tnfa
    • Replies: 0
    • Forum: Long Covid research
  7. SNT Gatchaman

    An aberrant immune–epithelial progenitor niche drives viral lung sequelae, 2024, Narasimhan et al.

    An aberrant immune–epithelial progenitor niche drives viral lung sequelae Narasimhan, Harish; Cheon, In Su; Qian, Wei; Hu, Sheng’en Shawn; Parimon, Tanyalak; Li, Chaofan; Goplen, Nick; Wu, Yue; Wei, Xiaoqin; Son, Young Min; Fink, Elizabeth; de Almeida Santos, Gislane; Tang, Jinyi; Yao, Changfu...
  8. SNT Gatchaman

    Preprint Inflammatory Cytokines Can Induce Synthesis Of Type-I Interferon, 2024, Sharma et al.

    Inflammatory Cytokines Can Induce Synthesis Of Type-I Interferon Nikhil Sharma; Xu Qi; Patricia Kessler; Ganes C. Sen Type I interferon (IFN) is induced in virus infected cells, secreted and it inhibits viral replication in neighboring cells. IFN is also an important player in many non-viral...
  9. SNT Gatchaman

    COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway, 2023, Mroueh et al.

    COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway Ali Mroueh; Walaa Fakih; Adrien Carmona; Antonin Trimaille; Kensuke Matsushita; Benjamin Marchandot; Abdul Wahid Qureshi; Dal-Seong Gong; Cyril Auger; Laurent Sattler...
    • SNT Gatchaman
    • Thread
    • coagulation covid-19 cytokines endothelial dysfunction enos il-1b il-6 nf-κb nitric oxide oxidative stress platelets redox tnf
    • Replies: 0
    • Forum: Long Covid research
  10. Mij

    Proximal immune-epithelial progenitor interactions drive chronic tissue sequelae post COVID-19, 2023, Harish Narasimhan et al

    Abstract The long-term health effects of SARS-CoV-2, termed Post-Acute Sequelae of COVID-19 (PASC), are quickly evolving into a major public health concern, but the underlying cellular and molecular etiology remain poorly defined. There is growing evidence that PASC is linked to abnormal immune...
    • Mij
    • Thread
    • anakinra baricitinib cd8 il-1b long covid t cells
    • Replies: 8
    • Forum: Long Covid research
  11. SNT Gatchaman

    Diminished vasculogenesis under inflammatory conditions is mediated by Activin A, 2023, Manohar-Sindhu et al.

    Diminished vasculogenesis under inflammatory conditions is mediated by Activin A Manohar-Sindhu, Sahana; Merfeld-Clauss, Stephanie; Goddard, Yana; March, Keith L.; Traktuev, Dmitry O. Severe inflammatory stress often leads to vessel rarefaction and fibrosis, resulting in limited tissue...
  12. SNT Gatchaman

    Proinflammatory Mediators, IL Interleukin-1β, TNF Tumor Necrosis Factor α, and Thrombin Directly Induce Capillary Tube Regression, 2020, Koller et al.

    Proinflammatory Mediators, IL Interleukin-1β, TNF Tumor Necrosis Factor α, and Thrombin Directly Induce Capillary Tube Regression Gretchen M. Koller; Christopher Schafer; Scott S. Kemp; Kalia N. Aguera; Prisca K. Lin; Joshua C. Forgy; Courtney T. Griffin; George E. Davis OBJECTIVE: In this...
  13. E

    Chronic inflammation, neutrophil activity, and autoreactivity splits long COVID, 2023, Woodruff et al

    Chronic inflammation, neutrophil activity, and autoreactivity splits long COVID Abstract While immunologic correlates of COVID-19 have been widely reported, their associations with post-acute sequelae of COVID-19 (PASC) remain less clear. Due to the wide array of PASC presentations...
  14. belbyr

    Preprint [Preprint] Exosome-associated Mitochondrial DNA Elevated in... ME/CFS and Stimulates... Microglia to Secrete IL-1β, 2023, Theoharides, Natelson et al

    Exosome-associated Mitochondrial DNA is Elevated in Patients with ME/CFS and Stimulates Human Cultured Microglia to Secrete IL-1β https://www.researchsquare.com/article/rs-154011/v1 Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating disease that presents...
    • belbyr
    • Thread
    • ben natelson exosomes il-1b il-1ß mtdna theoharides
    • Replies: 13
    • Forum: ME/CFS research
  15. Sly Saint

    Unravelling the nature of postexertional malaise in ME/CFS: the role of elastase, complement C4a and interleukin-1β 2010, Nijs et al

    Unravelling the nature of postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: the role of elastase, complement C4a and interleukin-1β Abstract Abstract. Nijs J, Van Oosterwijck J, Meeus M, Lambrecht L, Metzger K, Frémont M, Paul L (Vrije Universiteit Brussel...
    • Sly Saint
    • Thread
    • 2010 belgium c4a complement elastin il-1b il-1ß me/cfs nijs paper pem
    • Replies: 9
    • Forum: ME/CFS research
  16. Andy

    Animal Models for Neuroinflammation and Potential Treatment Methods, 2022, Tamura et al

    [This seems to be only very tenuously about ME/CFS] Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease of unknown etiology and without effective treatment options. The onset of ME/CFS is often associated with neuroinflammation following bacterial or...
    • Andy
    • Thread
    • animal model il-1b il-1ß minocycline neuroinflammation treatment
    • Replies: 4
    • Forum: ME/CFS research
  17. J

    Are Circulating FGF21 and NT-proBNP promising novel biomarkers in ME/CFS, 2020, Joan Charles Domingo et al

    Full title: Are Circulating FGF21 and NT-proBNP promising novel biomarkers in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome? https://www.liebertpub.com/doi/abs/10.1089/ars.2020.8230
  18. Andy

    Cytokine profiles in patients with Q fever fatigue syndrome, 2019, Raijmakers et al

    Paywalled at https://www.journalofinfection.com/article/S0163-4453(19)30027-1/fulltext
    • Andy
    • Thread
    • 2019 cytokines il-1b il-6 immunology me/cfs paper q fever q fever fatigue syndrome qfs raijmakers
    • Replies: 1
    • Forum: ME/CFS research
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