Multi-layered deep immune profiling, SARS-CoV-2 RNAemia and inflammation in unvaccinated COVID-19 individuals with persistent symptoms
Roberta Rovito, Valeria Bono, Nicolò Coianiz, Valentina Cazzetta, Sara Franzese, Joanna Mikulak, Clara Di Vito, Francesca Bai, Guillaume Beaudoin-Bussières...
Hyper-reactivity of CD8+ T cells and high expression of IL-3 correlates with occurrence and severity of Long-COVID
Renner; Stauffenberg; Paulus; Neumayer; Winter-Köhler; Buchtler; Schmalenberger; Blaas; Mohr; Pfeifer; Malfertheiner; Loew; Sester; Bals; Peterhoff; Schmidt; Mack
Following...
Cytokine Profile in Patients with Postacute Sequelae of COVID-19
Nathalie Ghorra; Alexandros Popotas; Tatiana Besse-Hammer; Anne Rogiers; Francis Corazza; Carole Nagant
The enduring impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease manifestation, COVID-19...
Abstract
Post-acute sequelae of COVID (PASC) persist in many patients for weeks and months after recovery from initial SARS-CoV-2 infection. Recent evidence suggests that pathological changes in skeletal muscle may contribute significantly to ongoing pain and fatigue, particularly...
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, heterogenous disease characterized by unexplained persistent fatigue and other features including cognitive impairment, myalgias, post-exertional malaise, and immune system dysfunction. Cytokines are present in...
Preprint
Plasma cytokine levels reveal deficiencies in IL-8 and gamma interferon in Long-COVID, 2022, Elizabeth S C P Williams et al
See post #8 for published version
Abstract
Up to half of individuals who contract SARS-CoV-2 develop symptoms of long-COVID approximately three months after...
https://www.frontiersin.org/articles/10.3389/fimmu.2021.700782/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE
Expression of CCR5 and its cognate ligands have been implicated in COVID-19 pathogenesis, consequently therapeutics directed against CCR5 are being...
Abstract
Background: Chronic fatigue syndrome (ME/CFS) is a complex disease frequently triggered by infections. IgG substitution may have therapeutic effect both by ameliorating susceptibility to infections and due to immunomodulatory effects.
Methods: We conducted a proof of concept open...
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-017-1161-4
Background
Investigations of activin family proteins as serum biomarkers for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). CFS/ME is a disease with complex, wide-ranging symptoms, featuring...
https://link.springer.com/article/10.1007%2Fs10096-018-3265-z
Eur J Clin Microbiol Infect Dis. 2018 May 26. doi: 10.1007/s10096-018-3265-z. [Epub ahead of print]
Interferon-γ and CXCL10 responses related to complaints in patients with Q fever fatigue syndrome.
Raijmakers RPH1,2, Jansen AFM3,4...
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