innate immune response

  1. SNT Gatchaman

    Preprint Systemic Multi-Omics … Reveals Interferon Response Heterogeneity & Links Lipid Metabolism to Immune Alterations in Severe COVID, 2025, Lira-Junior+

    Systemic Multi-Omics Analysis Reveals Interferon Response Heterogeneity and Links Lipid Metabolism to Immune Alterations in Severe COVID-19 Ronaldo Lira-Junior; Anoop Ambikan; Axel Cederholm; Ssefanit Rezene; Flora Mikaeloff; Sara Svensson Akusjarvi; Ahmet Yalcinkaya; Xi Chen; Maike Sperk...
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    • amino acids immunometabolic innate immune response interferon interferon-stimulated genes lipids metabolomics mitochondria monocytes neopterin neutrophils plasmalogen proteomics sphingolipids tryptophan
    • Replies: 1
    • Forum: Long Covid research
  2. SNT Gatchaman

    An ultra-early, transient interferon-associated innate immune response associates with protection from SARS-CoV-2 infection, 2024, Fenn+

    An ultra-early, transient interferon-associated innate immune response associates with protection from SARS-CoV-2 infection despite exposure Joe Fenn et 77 al BACKGROUND A proportion of individuals exposed to respiratory viruses avoid contracting detectable infection. We tested the hypothesis...
  3. SNT Gatchaman

    Review Type I interferons and endoplasmic reticulum stress in health and disease, 2020, Sprooten and Garg

    Type I interferons and endoplasmic reticulum stress in health and disease Sprooten; Garg Type I interferons (IFNs) comprise of pro-inflammatory cytokines created, as well as sensed, by all nucleated cells with the main objective of blocking pathogens-driven infections. Owing to this broad range...
  4. SNT Gatchaman

    The choroid plexus synergizes with immune cells during neuroinflammation, 2024, Xu et al.

    The choroid plexus synergizes with immune cells during neuroinflammation Huixin Xu; Peter Lotfy; Sivan Gelb; Aja Pragana; Christine Hehnly; Lillian I.J. Byer; Frederick B. Shipley; Miriam E. Zawadzki; Jin Cui; Liwen Deng; Milo Taylor; Mya Webb; Hart G.W. Lidov; Mark L. Andermann; Isaac M. Chiu...
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    • blood brain barrier blood csf barrier cerebrospinal fluid choroid plexus immune system innate immune response macrophages monocytes neuroinflammation neutrophils
    • Replies: 1
    • Forum: Other health news and research
  5. Mij

    Fibrin promotes oxidative stress and neuronal loss in traumatic brain injury via innate immune activation, 2024 Terry Dean et al

    Abstract Background Traumatic brain injury (TBI) causes significant blood-brain barrier (BBB) breakdown, resulting in the extravasation of blood proteins into the brain. The impact of blood proteins, especially fibrinogen, on inflammation and neurodegeneration post-TBI is not fully understood...
  6. SNT Gatchaman

    Persistent immune abnormalities discriminate post-COVID syndrome from convalescence, 2024, Sbierski-Kind et al.

    Persistent immune abnormalities discriminate post-COVID syndrome from convalescence Sbierski-Kind, Julia; Schlickeiser, Stephan; Feldmann, Svenja; Ober, Veronica; Grüner, Eva; Pleimelding, Claire; Gilberg, Leonard; Brand, Isabel; Weigl, Nikolas; Ahmed, Mohamed I. M.; Ibarra, Gerardo; Ruzicka...
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    • chemokines cytokines endotheliitis endothelium inflammation innate immune response long covid
    • Replies: 1
    • Forum: Long Covid research
  7. SNT Gatchaman

    A genetically modulated Toll-like-receptor-tolerant phenotype in peripheral blood cells of children with multisystem inflammatory syndrome, 2024, Khan

    A genetically modulated Toll-like-receptor-tolerant phenotype in peripheral blood cells of children with multisystem inflammatory syndrome. Rehan Khan; Weizhen Ji; Jeisac Guzman-Rivera; Abhilasha Madhvi; Tracy Andrews; Benjamin Richlin; Christian Suarez; Sunanda Gaur; William Cuddy; Aalok R...
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    • children gut permeability innate immune response khan long covid lysosomes mis-c mitochondria zonulin
    • Replies: 0
    • Forum: Long Covid research
  8. rvallee

    Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants, 2024, Towers et al

    Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants Nature, open access: https://www.nature.com/articles/s41564-023-01588-4 Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted in distinct lineages with enhanced...
  9. SNT Gatchaman

    Preprint Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19, 2024, Ashok et al.

    Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19 Deepthi Ashok; Ting Liu; Joseph Criscione; Meghana Prakash; Byunggik Kim; Julian Chow; Morgan Craney; Kyriakos Papanicolaou; Agnieszka Sidor; D. Brian Foster; Andrew Pekosz...
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    • arrhythmia cardiac cardiac function cytokines innate immune response interferon interferon-stimulated genes jak inhibitors jak-stat macrophages mitochondria reactive oxygen species
    • Replies: 0
    • Forum: Long Covid research
  10. Mij

    Single-cell RNA-Seq reveals intracellular microbial diversity within immune cells during SARS-CoV-2 infection and recovery, 2023, Sunita Yadav et al

    Highlights 76 bacterial species of 15 genera across healthy, COVID-19-positive, and recovered individuals Higher abundance of opportunistic intracellular bacteria in recovered group Higher microbial abundance within antigen-presenting cells of COVID-19 patients Differential microbial abundance...
    • Mij
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    • b cells covid dendritic cells innate immune response intracellular infection intracellular pathogen macrophages monocytes nk cells pbmc plasma cells platelets single-cell transcriptomics t cells
    • Replies: 6
    • Forum: Epidemics (including Covid-19, not Long Covid)
  11. SNT Gatchaman

    Preprint Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications, 2023, Mikulski et al.

    Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications Pawel Mikulski; Sahar S.H. Tehrani; Anna Kogan; Izma Abdul-Zani; Emer Shell; Brent J Ryan; Lars E.T. Jansen Interferon-γ (IFNγ) transiently activates genes involved in...
  12. SNT Gatchaman

    Sex-dependent differences in type I IFN-induced natural killer cell activation, 2023, Pujantell et al.

    Sex-dependent differences in type I IFN-induced natural killer cell activation Pujantell, Maria; Skenteris, Nikolaos-Taxiarchis; Claussen, Janna Marieke; Grünhagel, Benjamin; Thiele, Rebecca-Jo; Altfeld, Marcus Natural killer (NK) cells are important antiviral effector cells and also involved...
  13. SNT Gatchaman

    Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins, 2023, Frauenlob et al.

    Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins Frauenlob, Tobias; Neuper, Theresa; Regl, Christof; Schaepertoens, Veronika; Unger, Michael S.; Oswald, Anna-Lena; Dang, Hieu-Hoa; Huber, Christian G.; Aberger, Fritz; Wessler, Silja...
  14. SNT Gatchaman

    SARS-CoV-2 spike antigen-specific B cell and antibody responses in convalescent males and females with or without post-covid condition, 2023, Limoges+

    SARS-CoV-2 spike antigen-specific B cell and antibody responses in pre-vaccination period COVID-19 convalescent males and females with or without post-covid condition Limoges, Marc-André; Quenum, Akouavi Julite Irmine; Chowdhury, Mohammad Mobarak Hussain; Rexhepi, Fjolla; Namvarpour, Mozhdeh...
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    • b cells dysregulation humoral immune response innate immune response long covid sex differences spike protein t cells viral persistence
    • Replies: 2
    • Forum: Long Covid research
  15. SNT Gatchaman

    Persistent immune and clotting dysfunction detected in saliva and blood plasma after COVID-19, 2023, Jang et al.

    Persistent immune and clotting dysfunction detected in saliva and blood plasma after COVID-19 Hyesun Jang; Saibyasachi Choudhury; Yanbao Yu; Benjamin L. Sievers; Terri Gelbart; Harinder Singh; Stephen A. Rawlings; Amy Proal; Gene S. Tan; Yu Qian; Davey Smith; Marcelo Freire A growing number of...
  16. SNT Gatchaman

    Suppressed immune and metabolic responses to intestinal damage-associated microbial translocation in [ME/CFS], 2023, Uhde, Vernon et al.

    Suppressed immune and metabolic responses to intestinal damage-associated microbial translocation in myalgic encephalomyelitis/chronic fatigue syndrome Uhde; Indart; Green; Yolken; Cook; Shukla; Vernon; Alaedini The etiology and mechanism of myalgic encephalomyelitis/chronic fatigue syndrome...
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    • gut gut microbiome il-10 immune system innate immune response metabolism microbiome
    • Replies: 15
    • Forum: ME/CFS research
  17. Andy

    Review: Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response, 2019, Mohanty et al

    Paywalled at https://link.springer.com/article/10.1007%2Fs12079-019-00507-9 Sci Hub link, https://sci-hub.tw/https://link.springer.com/article/10.1007%2Fs12079-019-00507-9
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