interferon gamma

  1. SNT Gatchaman

    Preprint Heightened innate immunity may trigger chronic inflammation, fatigue and [PEM]…, 2025, Che, Hornig, Bateman, Klimas, Komaroff, Lipkin+

    Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by unexplained fatigue, post-exertional malaise (PEM), and cognitive dysfunction. ME/CFS patients often report...
    • SNT Gatchaman
    • Thread
    • amino acids calcium complement copper extracellular matrix fatty acid metabolism fatty acid oxidation gdf15 gut microbiome herv innate immune system integrins interferon gamma kynurenine lipid metabolism lipids metabolism serotonin tryptophan vegf
    • Replies: 5
    • Forum: ME/CFS research
  2. SNT Gatchaman

    Mast cells boost anti-tumor potency of MAIT cells via inflammasome-dependent secretion of IL-18, 2025, Fan et al.

    Mast cells boost anti-tumor potency of MAIT cells via inflammasome-dependent secretion of IL-18 Fan, Fanfan; Wang, Jun; Liu, Kun; Zhang, Shiyue; Gao, Jian; Li, Xiongfei; Ma, Jiaqiang; Zhao, Yue; Li, Teng; Su, Han; Yang, Xinfeng; Han, Han; Huang, Qingyuan; Zhang, Yiliang; Pan, Yunjian; Ye, Ting...
  3. SNT Gatchaman

    Protective role of anti-SARS-CoV-2 antibody responses against vital organ related long COVID symptoms, 2025, Yukari Magawa et al.

    Protective role of anti-SARS-CoV-2 antibody responses against vital organ related long COVID symptoms Yukari Magawa, Jhosiene; Jacintho, Lucas Cauê; Alves Ferreira, Marcelo; Ramos Oliveira, Jamille; Rahal Guaragna Machado, Rafael; Kuramoto Takara, Andreia; Moreno Lima de Oliveira, Renata...
  4. jnmaciuch

    Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19, Liu et al. 2020

    Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19 (2020) Yuying Liu, Jiadi Lv, Jiangning Liu, Man Li, Jing Xie, Qi Lv, Wei Deng, Nannan Zhou, Yabo Zhou, Jiangping Song, Peng Wang, Chuan Qin, Wei-Min Tong & Bo Huang Abstract Silent hypoxia has emerged as a unique...
  5. Andy

    Inhibition of the Na+-glucose transporter SGLT2 reduces glucose uptake and IFNγ release from activated human CD4+ T cells 2025 Jin et al

    Glucose uptake in activated CD4+ T cells is essential for increased metabolic needs, synthesis of biomolecules and proliferation. Although, facilitated glucose transport is the predominant route for glucose entry at the time of activation, here we demonstrate role for the sodium-dependent...
  6. jnmaciuch

    IFNγ causes mitochondrial dysfunction and oxidative stress in myositis, 2024, Abad et al.

    IFNγ causes mitochondrial dysfunction and oxidative stress in myositis Catalina Abad, Iago Pinal-Fernandez, Clement Guillou, Gwladys Bourdenet, Laurent Drouot, Pascal Cosette, Margherita Giannini, Lea Debrut, Laetitia Jean, Sophie Bernard, Damien Genty, Rachid Zoubairi, Isabelle Remy-Jouet...
    • jnmaciuch
    • Thread
    • ifny interferon gamma mitochondria mitochondrial architecture mitochondrial dysfunction mitochondrial myopathy myositis transcriptomics
    • Replies: 14
    • Forum: Other health news and research
  7. SNT Gatchaman

    Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation, 2025, White et al.

    Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation White, Zachary; Cabrera, Ivan; Mei, Linghan; Clevenger, Margarette; Ochoa-Raya, Andrea; Kapustka, Isabel; Dominguez, Joseph R.; Zhou, Jinyan; Koster, Kevin P.; Anwar, Shehata; Wang, Qianxun; Ng, Charles; Sagoshi...
  8. Nightsong

    Preprint A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma, 2025, Edwards, Cambridge and Cliff

    Abstract: Evidence bearing on possible mechanisms for the clinical syndrome of ME/CFS is reviewed. The evidence is used to argue for a hypothesis that centres on a form of persistent, inappropriate, ‘neuroimmune hypervigilance’ mediated primarily by T lymphocyte-macrophage interaction but...
    • Nightsong
    • Thread
    • cd64 fcγri igg iggr interferon interferon gamma jackie cliff jo cambridge jonathan edwards t cells
    • Replies: 663
    • Forum: ME/CFS research
  9. Jonathan Edwards

    Notice about a forthcoming paper: A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma

    Link to the thread on the preprint - 27 May 2025: A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma, 2025, Edwards, Cambridge and Cliff ****** I am hoping that the paper I have been writing with Jo Cambridge and Jackie Cliff will appear on Qeios tomorrow. If...
  10. jnmaciuch

    Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation, 2020, Seim et al.

    Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation Gretchen L Seim, Emily C Britt, Steven V John, Franklin J Yeo, Aaron R Johnson, Richard S Eisenstein, David J Pagliarini, Jing Fan Abstract In response to signals associated with...
  11. jnmaciuch

    Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages, 2018, Wang et al.

    Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity Feilong Wang ∙ Song Zhang ∙ Ryounghoon Jeon ∙ Ivan Vuckovic ∙ Xintong Jiang∙ Amir Lerman∙ Clifford D. Folmes ∙ Petras D. Dzeja ∙ Joerg Herrmann Highlights...
  12. forestglip

    Cytokine signature associated with disease severity in chronic fatigue syndrome patients, 2017, Montoya et al

    Cytokine signature associated with disease severity in chronic fatigue syndrome patients Jose G Montoya, Tyson H Holmes, Jill N Anderson, Holden T Maecker, Yael Rosenberg-Hasson, Ian J Valencia, Lily Chu, Jarred W Younger, Cristina M Tato, Mark M Davis Published: July 31, 2017 [Line breaks...
    • forestglip
    • Thread
    • cxcl9 ifny interferon gamma interferon-y me/cfs resistin tgf-β
    • Replies: 18
    • Forum: ME/CFS research
  13. forestglip

    Symptoms and Pathophysiology of Post-Acute Sequelae of SARS-CoV-2 (PASC): A Cohort Study, 2024, Robineau et al

    Symptoms and Pathophysiology of Post-Acute Sequelae of SARS-CoV-2 (PASC): A Cohort Study Olivier Robineau, Sophie Hüe, Mathieu Surenaud, Cédric Lemogne, Céline Dorival, Emmanuel Wiernik, Sebastian Brami, Jerome Nicol, Xavier de Lamballerie, Hélène Blanché, Jean-François Deleuze, Céline Ribet...
  14. pooriepoor91

    BioMapAI: Artificial Intelligence Multi-Omics Framework Modeling of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, 2024, Xiong et al.

    https://www.biorxiv.org/content/10.1101/2024.06.24.600378v1 BioMapAI: Artificial Intelligence Multi-Omics Framework Modeling of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome Ruoyun Xiong, Elizabeth Fleming, Ryan Caldwell, Suzanne D. Vernon, Lina Kozhaya, Courtney Gunter, Lucinda...
    • pooriepoor91
    • Thread
    • artificial intelligence bile acid biomapai gamma-delta t cells interferon interferon gamma lipids mait cells multi-omics
    • Replies: 18
    • Forum: ME/CFS research
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