isg15

  1. Hutan

    Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment, 2016, Blank +

    Link Highlights • Viruses induce depressive behavior and ISG15 expression at the blood-brain barrier • IFNAR1 expression on neural cells is not involved in IFN-β-induced sickness behavior • IFNAR1 expression on brain endothelial and epithelial cells drives behavioral changes • Brain...
  2. SNT Gatchaman

    [Preprint] Dysregulation of innate immunity and cellular metabolism through virus-induced deISGylation, 2025, Zhu et al.

    Dysregulation of innate immunity and cellular metabolism through virus-induced deISGylation Interferon-stimulated gene 15 (ISG15) regulates diverse cellular responses including antiviral immunity through its conjugation to proteins, a process known as ISGylation. Several pathogens, including...
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