Immunological synapse: structures, molecular mechanisms and therapeutic implications in disease
The immunological synapse (IS) serves as the fundamental architectural framework for direct interactions and secretory crosstalk between immune cells, as well as between immune cells and other...
https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00522-1
Highlights
• Female long COVID (LC) patients show heightened immune activation and inflammation
• Disrupted sex hormone levels differ between male and female LC patients
• Neuroinflammatory gene signatures may explain...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583111/
Abstract
Complement activation resulting in significant increases of C4a split product may be a marker of postexertional malaise in individuals with chronic fatigue syndrome (CFS). This study focused on identification of the transcriptional...
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