mapk

Highlights Mononuclear cells are primary drivers of the exercise response in skeletal muscle • Release of histamine from skeletal muscle during exercise from mast cells • Histamine receptor antagonists impair post-exercise muscle glycogen resynthesis • Exercise-induced transcriptional...

https://www.medrxiv.org/content/10.1101/2025.02.04.25320937v1.full.pdf+html New Precision Life preprint that was shared by Chris Ponting in Bluesky today. Looks very interesting.

Aquaporins: Gatekeepers of Fluid Dynamics in Traumatic Brain Injury Czyżewski, Wojciech; Litak, Jakub; Sobstyl, Jan; Mandat, Tomasz; Torres, Kamil; Staśkiewicz, Grzegorz Aquaporins (AQPs), particularly AQP4, play a crucial role in regulating fluid dynamics in the brain, impacting the...

Disuse-Induced Muscle Fatigue: Facts and Assumptions Sergeeva, Xenia V.; Lvova, Irina D.; Sharlo, Kristina A. Skeletal muscle unloading occurs during a wide range of conditions, from space flight to bed rest. The unloaded muscle undergoes negative functional changes, which include increased...

Inflammatory Cytokines Can Induce Synthesis Of Type-I Interferon Nikhil Sharma; Xu Qi; Patricia Kessler; Ganes C. Sen Type I interferon (IFN) is induced in virus infected cells, secreted and it inhibits viral replication in neighboring cells. IFN is also an important player in many non-viral...

Abstract Background and Objectives: The aetiology and pathomechanism of fibromyalgia syndrome 12 (FMS) as one of chronic pain syndromes still need to be further elucidated. Mitogen-activated protein kinase (MAPK) pathway has been proposed as a novel approach in pain management. Since the major...