melatonin

Chronic Fatigue Syndrome (CFS) represents a disabling condition characterized by persistent mental and physical fatigue, bodily discomfort and cognitive difficulties. To date the neural bases of CFS are poorly understood; however, mono-aminergic abnormalities, sleep–wake cycle changes and...

Targeted analysis of seven selected tryptophan-melatonin metabolites: Simultaneous quantification of plasma analytes using fast and sensitive UHPLC–MS/MS Kaleta; Kolitha; Novák; Rad; Bergquist; Ubhayasekera Tryptophan-derived metabolites, a group of neurotransmitters essential for various brain...

Abstract Spinal cord injury (SCI) is one of the most devastating and catastrophic types of injury, with high rates of mortality and disability. Ferroptosis has become the target of many major incurable human diseases. By inhibiting ferroptosis, melatonin (MT) can reduce the damage in various...

Abstract Mitochondrial homeostasis plays a major role in the progression of chronic inflammatory bone loss which has a complex pathogenesis with unsatisfactory therapeutic efficiency. Recently, melatonin has been shown to recipient mitochondrial function and bone formation. However, the effects...

https://link.springer.com/article/10.1007/s11011-024-01428-2 12-week melatonin intake attenuates cardiac autonomic dysfunction and oxidative stress in multiple sclerosis patients: a randomized controlled trial Research Published: 04 December 2024 Abstract Multiple sclerosis (MS) can induce...

Abstract Melatonin is a neurohormone that is mainly secreted by the pineal gland. It coordinates the work of the superior biological clock and consequently affects many processes in the human body. Disorders of the waking and sleeping period result in nervous system imbalance and generate...

Abstract Fibromyalgia syndrome (FMS) is a chronic widespread pain syndrome that is accompanied by fatigue, sleep disturbances, anxiety, depression, lack of concentration, and neurocognitive impairment. As the currently available drugs are not completely successful against these symptoms and...

The effect of melatonin on irritable bowel syndrome patients with and without sleep disorders: a randomized double-blinded placebo-controlled trial study 2023 Dinevari et al Abstract Background Irritable bowel syndrome (IBS) is one of the world's most common gastrointestinal (GI) disorders, and...

Cardiopulmonary and hematological effects of infrared LED photobiomodulation in the treatment of SARS-COV2 Pâmela Camila Pereira, Carlos José de Lima, Adriana Barrinha Fernandes, Renato Amaro Zângaro, Antonio Balbin Villaverde Background COVID-19 disease is caused by SARS-CoV-2 which can...

Abstract Clinical sequelae and symptoms for a considerable number of COVID-19 patients can linger for months beyond the acute stage of SARS-CoV-2 infection, “long COVID”. Among the long-term consequences of SARS-CoV-2 infection, cognitive issues (especially memory loss or “brain fog”), chronic...

An old paper Korszun, A., L. Sackett-Lundeen, E. Papadopoulos, C. Brucksch, L. Masterson, N. C. Engelberg, E. Haus, M. A. Demitrack, and L. Crofford. “Melatonin Levels in Women with Fibromyalgia and Chronic Fatigue Syndrome.” The Journal of Rheumatology 26, no. 12 (December 1999): 2675–80...

Preprint Effect of Melatonin Plus Zinc Supplementation on Fatigue Perception in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial " Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, multisystem, and...

Full title: Multiple Sclerosis: Melatonin, Orexin, and Ceramide Interact with Platelet Activation Coagulation Factors and Gut-Microbiome-Derived Butyrate in the Circadian Dysregulation of Mitochondria in Glia and Immune Cells Open access, https://www.mdpi.com/1422-0067/20/21/5500/htm

High sensitivity and interindividual variability in the response of the human circadian system to evening light Andrew J. K. Phillips, Parisa Vidafar, Angus C. Burns, Elise M. McGlashan, Clare Anderson, Shantha M. W. Rajaratnam, Steven W. Lockley, and Sean W. Cain Significance Electric...

Article: " Bioglan homeopathic melatonin Big pharmaceutical companies, or 'big pharma', are synonymous with big medical production, big money and a big impact on the type of healthcare products we can access. One thing that's rarely expected from big pharma is homeopathic cures, which are more...